Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma.
about
Beyond high-dose methotrexate and brain radiotherapy: novel targets and agents for primary CNS lymphomaMantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agentsA small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomasPIM kinases as potential therapeutic targets in a subset of peripheral T cell lymphoma cases.Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinomaSIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.mTOR-Dependent and Independent Survival Signaling by PI3K in B Lymphocytes.Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia.Combination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cellsBiological effects of the Pim kinase inhibitor, SGI-1776, in multiple myeloma.Combination of Pim kinase inhibitor SGI-1776 and bendamustine in B-cell lymphoma.Pim kinases in hematological malignancies: where are we now and where are we going?The activation loop tyrosine 823 is essential for the transforming capacity of the c-Kit oncogenic mutant D816V.Pim kinase isoforms: devils defending cancer cells from therapeutic and immune attacks.mTOR kinase-dependent, but raptor-independent regulation of downstream signaling is important for cell cycle exit and myogenic differentiation.Synthesis and Biological Evaluation of Pyrazolo[1,5-a]pyrimidine Compounds as Potent and Selective Pim-1 Inhibitors.Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia.PIM-1 kinase inhibitor SMI-4a exerts antitumor effects in chronic myeloid leukemia cells by enhancing the activity of glycogen synthase kinase 3β.A novel, dual pan-PIM/FLT3 inhibitor SEL24 exhibits broad therapeutic potential in acute myeloid leukemia.Microenvironment-induced PIM kinases promote CXCR4-triggered mTOR pathway required for chronic lymphocytic leukaemia cell migration.
P2860
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P2860
Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Transcription and translation ...... -1776 in mantle cell lymphoma.
@en
Transcription and translation ...... -1776 in mantle cell lymphoma.
@nl
type
label
Transcription and translation ...... -1776 in mantle cell lymphoma.
@en
Transcription and translation ...... -1776 in mantle cell lymphoma.
@nl
prefLabel
Transcription and translation ...... -1776 in mantle cell lymphoma.
@en
Transcription and translation ...... -1776 in mantle cell lymphoma.
@nl
P2093
P2860
P1433
P1476
Transcription and translation ...... -1776 in mantle cell lymphoma.
@en
P2093
L Jeffrey Medeiros
Lisa S Chen
Qingshan Yang
Sattva S Neelapu
Varsha Gandhi
P2860
P304
P356
10.1182/BLOOD-2012-02-412643
P407
P577
2012-09-06T00:00:00Z