Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations.
about
Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide productionIdentification of caspases that cleave presenilin-1 and presenilin-2Presenilin is the molecular target of acidic γ-secretase modulators in living cells.The 28-amino acid form of an APLP1-derived Abeta-like peptide is a surrogate marker for Abeta42 production in the central nervous system.Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1Molecular genetics of Alzheimer's disease: an update.Secretion of the Notch-1 Abeta-like peptide during Notch signaling.Insensitivity to Abeta42-lowering nonsteroidal anti-inflammatory drugs and gamma-secretase inhibitors is common among aggressive presenilin-1 mutations.A unifying hypothesis of Alzheimer's disease. III. Risk factors.Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure.Staurosporine-induced activation of caspase-3 is potentiated by presenilin 1 familial Alzheimer's disease mutations in human neuroglioma cells.
P2860
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P2860
Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Proteolytic processing of pres ...... ith or without PS-1 mutations.
@en
Proteolytic processing of presenilin-1
@nl
type
label
Proteolytic processing of pres ...... ith or without PS-1 mutations.
@en
Proteolytic processing of presenilin-1
@nl
prefLabel
Proteolytic processing of pres ...... ith or without PS-1 mutations.
@en
Proteolytic processing of presenilin-1
@nl
P2093
P2860
P1433
P1476
Proteolytic processing of pres ...... ith or without PS-1 mutations.
@en
P2093
Hendriks L
Kametani F
P2860
P304
P356
10.1016/S0014-5793(97)01378-1
P407
P577
1997-11-01T00:00:00Z