p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.
about
Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cellsInduction of p57(KIP2) expression by p73beta.MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-MThe transcriptional repressor ZEB regulates p73 expression at the crossroad between proliferation and differentiationOncogenic Intra-p53 Family Member Interactions in Human CancersOncogenic MicroRNAs: Key Players in Malignant TransformationInvolvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ)Smoking, p53 mutation, and lung cancerThe role of tumor suppressor p53 in the antioxidant defense and metabolismThe rebel angel: mutant p53 as the driving oncogene in breast cancer.Gain of function of mutant p53: R282W on the peak?The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome SystemTranscriptional dysregulation of the p73L / p63 / p51 / p40 / KET gene in human squamous cell carcinomas: expression of Delta Np73L, a novel dominant-negative isoform, and loss of expression of the potential tumour suppressor p51Arsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligasep73 as a pharmaceutical target for cancer therapyFunctional interplay between MDM2, p63/p73 and mutant p53Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.Two p53 tetramers bind one consensus DNA response elementOverexpressed TP73 induces apoptosis in medulloblastomaEffects of MDM2, MDM4 and TP53 codon 72 polymorphisms on cancer risk in a cohort study of carriers of TP53 germline mutations.p73 competes with p53 and attenuates its response in a human ovarian cancer cell line.Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B.Interactions of the p53 protein family in cellular stress response in gastrointestinal tumorsp53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation.p63 and p73 in tumor suppression and promotion.Germline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer riskMDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 functionp53 associates with and targets Delta Np63 into a protein degradation pathwaySynthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasisAutoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoterp53 inactivation upregulates p73 expression through E2F-1 mediated transcriptionmicroRNAs: short non-coding bullets of gain of function mutant p53 proteins.Mutant p53 protein is targeted by arsenic for degradation and plays a role in arsenic-mediated growth suppression.IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo.p73 in Cancer.Propagation of aggregated p53: Cross-reaction and coaggregation vs. seeding.Mechanism of initiation of aggregation of p53 revealed by Φ-value analysisThe dilution effect and the importance of selecting the right internal control genes for RT-qPCR: a paradigmatic approach in fetal sheep.p53 Family: Role of Protein Isoforms in Human Cancer.
P2860
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P2860
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.
@en
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.
@nl
type
label
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.
@en
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.
@nl
prefLabel
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.
@en
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.
@nl
P2860
P356
P1476
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells
@en
P2093
P2860
P304
P356
10.1128/MCB.19.2.1438
P407
P577
1999-02-01T00:00:00Z