Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.
about
Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cellsXRCC1 co-localizes and physically interacts with PCNAXRCC1 is required for DNA single-strand break repair in human cells.Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genesXRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damageEsc4/Rtt107 and the control of recombination during replication.The structural basis of XRCC1-mediated DNA repairTumor growth is suppressed in mice expressing a truncated XRCC1 proteinDNA repair mechanisms in plants: crucial sensors and effectors for the maintenance of genome integrityAssociation between DNA repair gene polymorphisms and risk of glioma: a systematic review and meta-analysisPolymorphisms in DNA repair genes and susceptibility to glioma in a chinese populationNuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLSCommon genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibilityAssociation Between Twelve Polymorphisms in Five X-ray Repair Cross-complementing Genes and the Risk of Urological Neoplasms: A Systematic Review and Meta-AnalysisDNA repair gene XRCC1 polymorphisms and bladder cancer risk.X-ray repair cross complementing protein 1 in base excision repair.Genetic polymorphisms in DNA repair genes as modulators of Hodgkin disease risk.Influence of XRCC1 Genetic Polymorphisms on Ionizing Radiation-Induced DNA Damage and Repair.Spatial and temporal cellular responses to single-strand breaks in human cells.XRCC1 Arg194Trp and Arg280His polymorphisms increase bladder cancer risk in Asian population: evidence from a meta-analysisVariation in base excision repair capacity.Hodgkin lymphoma risk: role of genetic polymorphisms and gene-gene interactions in DNA repair pathways.Functional polymorphisms of base excision repair genes XRCC1 and APEX1 predict risk of radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy.The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function.In vitro and in vivo studies on the generation of the primary T-cell receptor repertoire.The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiencyCommentary: DNA base excision repair defects in human pathologies.A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage.Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time.XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks.XRCC1 and base excision repair balance in response to nitric oxideGenetic variation in XRCC1, sun exposure, and risk of skin cancer.Advances in the understanding of susceptibility to treatment-related acute myeloid leukaemia.Base excision repair, aging and health span.HPV prevalence and genetic predisposition to cervical cancer in Saudi ArabiaXRCC1 protects against the lethality of induced oxidative DNA damage in nondividing neural cellsDamage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitylation after degradation of poly(ADP-ribose).Strategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced CytotoxicityXRCC1 interacts with the p58 subunit of DNA Pol alpha-primase and may coordinate DNA repair and replication during S phase.
P2860
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P2860
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.
@en
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.
@nl
type
label
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.
@en
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.
@nl
prefLabel
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.
@en
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.
@nl
P2093
P2860
P1476
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.
@en
P2093
Angela Thistlethwaite
Keith W Caldecott
Richard M Taylor
P2860
P304
P356
10.1128/MCB.22.8.2556-2563.2002
P407
P577
2002-04-01T00:00:00Z