Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling.
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The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolismUnderstanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environmentMitochondrial Dysfunction and Disturbed Coherence: Gate to Cancer.Adipocytes: impact on tumor growth and potential sites for therapeutic interventionOncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discoveryUnderstanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironmentImaging metabolic heterogeneity in cancerCancer: An Oxidative Crosstalk between Solid Tumor Cells and Cancer Associated FibroblastsA strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox processIntratumoral lactate metabolism in Barrett's esophagus and adenocarcinoma.MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion.Weak stromal Caveolin-1 expression in colorectal liver metastases predicts poor prognosis after hepatectomy for liver-only colorectal metastases.Concordant release of glycolysis proteins into the plasma preceding a diagnosis of ER+ breast cancer.Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers.The nutritional phenome of EMT-induced cancer stem-like cellsObesity and cancer--mechanisms underlying tumour progression and recurrenceCaveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblastsGli1 mediates lung cancer cell proliferation and Sonic Hedgehog-dependent mesenchymal cell activation.Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".Cancer therapeutics: time to swim downstream?Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connectionCaveolin-1 expression is elevated in claudin-low mammary tumor cells.Decreased PCSK9 expression in human hepatocellular carcinoma.Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysisFBXW7 negatively regulates ENO1 expression and function in colorectal cancer.Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drugMetabolic Plasticity in Cancer Cells: Reconnecting Mitochondrial Function to Cancer Control.Tumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma.Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary glandMitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cellsBRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies.Altered energy metabolism in cancer: a unique opportunity for therapeutic intervention.Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma.Breast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition.Obesity, metabolism and the microenvironment: Links to cancerOncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.Genetic alterations and epigenetic alterations of cancer-associated fibroblasts.
P2860
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P2860
Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Glycolytic cancer associated f ...... epithelial metabolic coupling.
@en
Glycolytic cancer associated f ...... epithelial metabolic coupling.
@nl
type
label
Glycolytic cancer associated f ...... epithelial metabolic coupling.
@en
Glycolytic cancer associated f ...... epithelial metabolic coupling.
@nl
prefLabel
Glycolytic cancer associated f ...... epithelial metabolic coupling.
@en
Glycolytic cancer associated f ...... epithelial metabolic coupling.
@nl
P2093
P50
P356
P1433
P1476
Glycolytic cancer associated f ...... epithelial metabolic coupling.
@en
P2093
Alessandro Fatatis
Barbara Chiavarina
Gemma Migneco
Neal Flomenberg
Remedios Castello-Cros
Richard G Pestell
Stephanos Pavlides
P304
P356
10.4161/CC.9.12.11989
P50
P577
2010-06-15T00:00:00Z