Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis
about
Chinese Herbs Interfering with Cancer Reprogramming MetabolismLactate Contribution to the Tumor Microenvironment: Mechanisms, Effects on Immune Cells and Therapeutic RelevanceInterplay Between Metabolism and Oncogenic Process: Role of microRNAsBreast Cancer-Associated Fibroblasts: Where We Are and Where We Need to GoAutophagy in stem cells.Oncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discoveryInterplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapyEffects of shear stresses and antioxidant concentrations on the production of reactive oxygen species in lung cancer cellsMitochondria and cancerInteractions between exosomes from breast cancer cells and primary mammary epithelial cells leads to generation of reactive oxygen species which induce DNA damage response, stabilization of p53 and autophagy in epithelial cells.Weak stromal Caveolin-1 expression in colorectal liver metastases predicts poor prognosis after hepatectomy for liver-only colorectal metastases.Loss of stromal caveolin-1 expression: a novel tumor microenvironment biomarker that can predict poor clinical outcomes for pancreatic cancer.Mitochondrial proteomics of nasopharyngeal carcinoma metastasisCatabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.Loss of stromal caveolin-1 expression in colorectal cancer predicts poor survivalFamine versus feast: understanding the metabolism of tumors in vivo.Endothelial cell metabolism in normal and diseased vasculature.Mitochondrial DNA copy number in peripheral blood and melanoma risk.Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connectionLithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo.Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolismUsing the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone productionGlutaminolysis and autophagy in cancerTwo-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cellsAutophagy in pancreatic cancer pathogenesis and treatmentCorrelation between cell migration and reactive oxygen species under electric field stimulation.Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer modelsThe study of energy metabolism in bladder cancer cells in co-culture conditions using a microfluidic chip.Treatment of a chemoresistant neuroblastoma cell line with the antimalarial ozonide OZ513.Oxidized ATM promotes abnormal proliferation of breast CAFs through maintaining intracellular redox homeostasis and activating the PI3K-AKT, MEK-ERK, and Wnt-β-catenin signaling pathways.Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth.CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis.Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.Sickness behavior induced by cisplatin chemotherapy and radiotherapy in a murine head and neck cancer model is associated with altered mitochondrial gene expressionKetone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells.
P2860
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P2860
Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Warburg meets autophagy: cance ...... ophagy, and aerobic glycolysis
@ast
Warburg meets autophagy: cance ...... ophagy, and aerobic glycolysis
@en
type
label
Warburg meets autophagy: cance ...... ophagy, and aerobic glycolysis
@ast
Warburg meets autophagy: cance ...... ophagy, and aerobic glycolysis
@en
prefLabel
Warburg meets autophagy: cance ...... ophagy, and aerobic glycolysis
@ast
Warburg meets autophagy: cance ...... ophagy, and aerobic glycolysis
@en
P2093
P2860
P50
P356
P1476
Warburg meets autophagy: cance ...... ophagy, and aerobic glycolysis
@en
P2093
Diana Whitaker-Menezes
Federica Sotgia
Isabelle Mercier
Michael P Lisanti
Richard G Pestell
Stephanos Pavlides
P2860
P304
P356
10.1089/ARS.2011.4243
P577
2011-11-17T00:00:00Z