Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2 - Wikidata - awgldk - TriplyDB

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

http://www.wikidata.org/entity/Q39696685

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Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels Molecular targets for antiepileptic drug development Electrical resonance with voltage-gated ion channels: perspectives from biophysical mechanisms and neural electrophysiology Modern concepts concerning the origin of the heartbeat.Cortical HCN channels: function, trafficking and plasticity Essential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variability Two types of interneurons in the mouse lateral geniculate nucleus are characterized by different h-current density Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potential Mechanisms of sudden unexplained death in epilepsy Pacemaker activity of the human sinoatrial node: an update on the effects of mutations in HCN4 on the hyperpolarization-activated current Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4 Enhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase Postnatal expression pattern of HCN channel isoforms in thalamic neurons: relationship to maturation of thalamocortical oscillations.The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart.The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains.Enhanced GABAA-Mediated Tonic Inhibition in Auditory Thalamus of Rats with Behavioral Evidence of Tinnitus.Mechanotransduction and hyperpolarization-activated currents contribute to spontaneous activity in mouse vestibular ganglion neurons Functional contributions of HCN channels in the primary auditory neurons of the mouse inner ear.HCN channels expressed in the inner ear are necessary for normal balance function.Local anesthetic inhibits hyperpolarization-activated cationic currents Subunit-specific effects of isoflurane on neuronal Ih in HCN1 knockout mice.Suppression of ih contributes to propofol-induced inhibition of mouse cortical pyramidal neurons.Dendritic HCN channels shape excitatory postsynaptic potentials at the inner hair cell afferent synapse in the mammalian cochlea Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4 Absence epilepsy in apathetic, a spontaneous mutant mouse lacking the h channel subunit, HCN2 Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy.Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice.Selective participation of somatodendritic HCN channels in inhibitory but not excitatory synaptic integration in neurons of the subthalamic nucleus.Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy A molecular signature of tissues with pacemaker activity in the heart and upper urinary tract involves coexpressed hyperpolarization-activated cation and T-type Ca2+ channels.Hidden in plain sight: spike-wave discharges in mouse inbred strains.The pelvis-kidney junction contains HCN3, a hyperpolarization-activated cation channel that triggers ureter peristalsis.Distinct expression patterns of HCN channels in HL-1 cardiomyocytes.Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy.The Ih Channel Gene Promotes Synaptic Transmission and Coordinated Movement in Drosophila melanogaster.Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia.Cellular and network mechanisms of spike-wave seizures.

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Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

http://www.wikidata.org/entity/Q39696685

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

@en

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2.

@nl

type

label

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

@en

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2.

@nl

prefLabel

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

@en

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2.

@nl

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The EMBO Journal

P1476

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

@en

P2093

Andreas Ludwig

http://www.w3.org/2001/XMLSchema#string

Anke Langebartels

http://www.w3.org/2001/XMLSchema#string

Carsten Wotjak

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Christian Wahl

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Franz Hofmann

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Hans-Christian Pape

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Juliane Stieber

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Kenneth R Chien

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Knut Holthoff

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Marike Lancel

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P2860

Two pacemaker channels from human heart with profoundly different activation kinetics

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain

Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis

Thalamocortical oscillations in the sleeping and aroused brain

Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node.

Mibefradil block of cloned T-type calcium channels.

Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS.

Morphological and membrane characteristics of spider and spindle cells isolated from rabbit sinus node.

Neuronal circuitry of thalamocortical epilepsy and mechanisms of antiabsence drug action.

Differential distribution of four hyperpolarization-activated cation channels in mouse brain.

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216-224

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scholarly article

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10.1093/EMBOJ/CDG032

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2

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22

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Arthur Konnerth

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2003-01-01T00:00:00Z

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10962871

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12514127

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140107

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