Metabolic activities of metronidazole-sensitive and -resistant strains of Helicobacter pylori: repression of pyruvate oxidoreductase and expression of isocitrate lyase activity correlate with resistance.
about
Complete genome sequence of the oral pathogenic Bacterium porphyromonas gingivalis strain W83Nitroimidazoles for the treatment of TB: past, present and futureEnzymes associated with reductive activation and action of nitazoxanide, nitrofurans, and metronidazole in Helicobacter pylori.Response to metronidazole and oxidative stress is mediated through homeostatic regulator HsrA (HP1043) in Helicobacter pylori.Mutations to essential orphan response regulator HP1043 of Helicobacter pylori result in growth-stage regulatory defects.Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni.Flavodoxin:quinone reductase (FqrB): a redox partner of pyruvate:ferredoxin oxidoreductase that reversibly couples pyruvate oxidation to NADPH production in Helicobacter pylori and Campylobacter jejuni.Treatment of Helicobacter pylori infection: current status and future concepts.Metabolism and genetics of Helicobacter pylori: the genome era.Isolation of nitrofurantoin-resistant mutants of nitroreductase-producing Clostridium sp. strains from the human intestinal tract.Helicobacter pylori porCDAB and oorDABC genes encode distinct pyruvate:flavodoxin and 2-oxoglutarate:acceptor oxidoreductases which mediate electron transport to NADPHelicobacter pylori physiology predicted from genomic comparison of two strains.Review article: nitroimidazole resistance in Helicobacter pylori.Lipoic acid metabolism in microbial pathogens.Insertion of mini-IS605 and deletion of adjacent sequences in the nitroreductase (rdxA) gene cause metronidazole resistance in Helicobacter pylori NCTC11637.Analysis of rdxA and involvement of additional genes encoding NAD(P)H flavin oxidoreductase (FrxA) and ferredoxin-like protein (FdxB) in metronidazole resistance of Helicobacter pylori.Mechanism of metronidazole resistance in Helicobacter pylori: comparison of the rdxA gene sequences in 30 strains.HP0333, a member of the dprA family, is involved in natural transformation in Helicobacter pylori.Another unusual type of citric acid cycle enzyme in Helicobacter pylori: the malate:quinone oxidoreductase.Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pyloriAssociation of metronidazole resistance and natural competence in Helicobacter pylori.The tricarboxylic acid cycle of Helicobacter pylori.Development of an interleukin-12-deficient mouse model that is permissive for colonization by a motile KE26695 strain of Helicobacter pyloriComplexomics study of two Helicobacter pylori strains of two pathological origins: potential targets for vaccine development and new insight in bacteria metabolism.Helicobacter pylori detection and antimicrobial susceptibility testing.Characterization of a ComE3 homologue essential for DNA transformation in Helicobacter pylori.Ethnicity association of Helicobacter pylori virulence genotype and metronidazole susceptibilityIn vitro antibacterial activity of acyl-lysyl oligomers against Helicobacter pylori.Proteomic analysis of a NAP1 Clostridium difficile clinical isolate resistant to metronidazole.Optimal therapy for Helicobacter pylori infections.Subpopulations of Helicobacter pylori are responsible for discrepancies in the outcome of nitroimidazole susceptibility testing.Metronidazole activation is mutagenic and causes DNA fragmentation in Helicobacter pylori and in Escherichia coli containing a cloned H. pylori RdxA(+) (Nitroreductase) gene.Systematic identification of selective essential genes in Helicobacter pylori by genome prioritization and allelic replacement mutagenesisMetabolic pathways for cytotoxic end product formation from glutamate- and aspartate-containing peptides by Porphyromonas gingivalis.Genome-scale metabolic model of Helicobacter pylori 26695.A redox basis for metronidazole resistance in Helicobacter pyloriLon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in Helicobacter pylori.Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase.Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases.
P2860
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P2860
Metabolic activities of metronidazole-sensitive and -resistant strains of Helicobacter pylori: repression of pyruvate oxidoreductase and expression of isocitrate lyase activity correlate with resistance.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Metabolic activities of metron ...... ity correlate with resistance.
@en
Metabolic activities of metron ...... ity correlate with resistance.
@nl
type
label
Metabolic activities of metron ...... ity correlate with resistance.
@en
Metabolic activities of metron ...... ity correlate with resistance.
@nl
prefLabel
Metabolic activities of metron ...... ity correlate with resistance.
@en
Metabolic activities of metron ...... ity correlate with resistance.
@nl
P2093
P2860
P1476
Metabolic activities of metron ...... ity correlate with resistance.
@en
P2093
Hoffman PS
Veldhuyzen van Zanten SJ
P2860
P304
P356
10.1128/JB.178.16.4822-4829.1996
P577
1996-08-01T00:00:00Z