Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells.
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Autophagy, mitochondria and oxidative stress: cross-talk and redox signallingParkinson's Disease: The Mitochondria-Iron LinkFeatures of alpha-synuclein that could explain the progression and irreversibility of Parkinson's diseaseAgeing and Parkinson's disease: why is advancing age the biggest risk factor?Inflammation and α-synuclein's prion-like behavior in Parkinson's disease--is there a link?Human A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neuronsC-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.Alpha-Synuclein Oligomers-Neurotoxic Molecules in Parkinson's Disease and Other Lewy Body DisordersPreclinical Metabolism, Pharmacokinetics and In Vivo Analysis of New Blood-Brain-Barrier Penetrant Fingolimod Analogues: FTY720-C2 and FTY720-MitoxyRapamycin improves motor function, reduces 4-hydroxynonenal adducted protein in brain, and attenuates synaptic injury in a mouse model of synucleinopathyNovel FTY720-Based Compounds Stimulate Neurotrophin Expression and Phosphatase Activity in Dopaminergic Cells.Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells.The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicityDirect observation of the interconversion of normal and toxic forms of α-synucleinMitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection.TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease.Effects of impaired membrane interactions on α-synuclein aggregation and neurotoxicityMitochondrial Ca(2+) and neurodegenerationParkinson's disease and autophagy.Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein.α-Synuclein and mitochondria: partners in crime?Dopamine Cytotoxicity Involves Both Oxidative and Nonoxidative Pathways in SH-SY5Y Cells: Potential Role of Alpha-Synuclein Overexpression and Proteasomal Inhibition in the Etiopathogenesis of Parkinson's DiseaseThe biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's diseaseMitochondria, calcium, and endoplasmic reticulum stress in Parkinson's disease.Pathways towards an effective immunotherapy for Parkinson's diseaseInflammation and adaptive immunity in Parkinson's disease.αSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson's Disease?Perturbed mitochondrial Ca2+ signals as causes or consequences of mitophagy induction.Iron in neurodegenerative disorders of protein misfolding: a case of prion disorders and Parkinson's disease.Association of glycogen synthase kinase-3β with Parkinson's disease (review).The centrality of mitochondria in the pathogenesis and treatment of Parkinson's disease.A mitocentric view of Parkinson's disease.Defective autophagy in Parkinson's disease: lessons from genetics.Effects of Alpha-Synuclein on Primary Spinal Cord Neurons Associated with Apoptosis and CNTF Expression.α-Synuclein Over-Expression Induces Increased Iron Accumulation and Redistribution in Iron-Exposed Neurons.Knockdown of α-synuclein in cerebral cortex improves neural behavior associated with apoptotic inhibition and neurotrophin expression in spinal cord transected rats.α-Synuclein-induced mitochondrial dysfunction in isolated preparation and intact cells: implications in the pathogenesis of Parkinson's disease.Neuromelanin enhances the toxicity of α-synuclein in SK-N-SH cells.Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.Alpha-synuclein mediates alterations in membrane conductance: a potential role for alpha-synuclein oligomers in cell vulnerability.
P2860
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P2860
Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Alpha-synuclein overexpression ...... in human neuroblastoma cells.
@en
Alpha-synuclein overexpression ...... in human neuroblastoma cells.
@nl
type
label
Alpha-synuclein overexpression ...... in human neuroblastoma cells.
@en
Alpha-synuclein overexpression ...... in human neuroblastoma cells.
@nl
prefLabel
Alpha-synuclein overexpression ...... in human neuroblastoma cells.
@en
Alpha-synuclein overexpression ...... in human neuroblastoma cells.
@nl
P2093
P1476
Alpha-synuclein overexpression ...... in human neuroblastoma cells.
@en
P2093
Arti Parihar
Makoto Hashimoto
Masayo Fujita
Mordhwaj S Parihar
Pedram Ghafourifar
P304
P356
10.1016/J.BIOCEL.2009.05.008
P577
2009-05-19T00:00:00Z