Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues.
about
Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2Role of Nrf2 in oxidative stress and toxicityAdvances in mechanisms of anti-oxidationCullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic ImplicationsRedox Modulating NRF2: A Potential Mediator of Cancer Stem Cell ResistanceMolecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease interventionNrf2 and Notch Signaling in Lung Cancer: Near the CrossroadEpigenetic regulation of Keap1-Nrf2 signalingStress-activated cap'n'collar transcription factors in aging and human diseaseKaposi's sarcoma-associated herpesvirus induces Nrf2 activation in latently infected endothelial cells through SQSTM1 phosphorylation and interaction with polyubiquitinated Keap1The complexity of the Nrf2 pathway: beyond the antioxidant responseNrf2 and NF-κB and Their Concerted Modulation in Cancer Pathogenesis and ProgressionThe Keap1-Nrf2 system in cancers: stress response and anabolic metabolismCytoprotection "gone astray": Nrf2 and its role in cancerGenetic disruption of KEAP1/CUL3 E3 ubiquitin ligase complex components is a key mechanism of NF-kappaB pathway activation in lung cancer.Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP miceNrf2: friend or foe for chemoprevention?The Keap1-Nrf2 pathway: promising therapeutic target to counteract ROS-mediated damage in cancers and neurodegenerative diseases.High-resolution profiles of gene expression and DNA methylation highlight mitochondrial modifications during early embryonic development.Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.Targeted deletion of Nrf2 reduces urethane-induced lung tumor development in mice.Methylation of the KEAP1 gene promoter region in human colorectal cancerNRF2 and cancer: the good, the bad and the importance of context.Association of Nrf2 polymorphism haplotypes with acute lung injury phenotypes in inbred strains of mice.Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.Targeting NRF2 signaling for cancer chemoprevention.Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts.Relationship between air pollution, NFE2L2 gene polymorphisms and childhood asthma in a Hungarian population.KEAP1 gene mutations and NRF2 activation are common in pulmonary papillary adenocarcinoma.Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405.Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair.Oxidative stress induced lung cancer and COPD: opportunities for epigenetic therapy.Bortezomib induces heme oxygenase-1 expression in multiple myelomaNrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesisAberrant Keap1 methylation in breast cancer and association with clinicopathological features.Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression.Role of Nrf2 and Autophagy in Acute Lung InjuryGenomic structure and variation of nuclear factor (erythroid-derived 2)-like 2Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigenetics
P2860
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P2860
Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Hypermethylation of the Keap1 ...... lines and lung cancer tissues.
@en
Hypermethylation of the Keap1 ...... lines and lung cancer tissues.
@nl
type
label
Hypermethylation of the Keap1 ...... lines and lung cancer tissues.
@en
Hypermethylation of the Keap1 ...... lines and lung cancer tissues.
@nl
prefLabel
Hypermethylation of the Keap1 ...... lines and lung cancer tissues.
@en
Hypermethylation of the Keap1 ...... lines and lung cancer tissues.
@nl
P2093
P1476
Hypermethylation of the Keap1 ...... lines and lung cancer tissues.
@en
P2093
Deshan Zhou
Fengqing Ji
Haimei Sun
Huiqin Jiao
P304
P356
10.1016/J.BBRC.2008.06.004
P50
P577
2008-06-12T00:00:00Z