E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence.
about
Balance between MKK6 and MKK3 mediates p38 MAPK associated resistance to cisplatin in NSCLCGnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines.Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradationAKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.MKP1 mediates chemosensitizer effects of E1a in response to cisplatin in non-small cell lung carcinoma cells.E1a promotes c-Myc-dependent replicative stress: implications in glioblastoma radiosensitization.P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance.Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation.MKP1: Jekyll and Hyde for E1A.A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses.
P2860
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P2860
E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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name
E1a gene expression blocks the ...... in v-H-Ras-induced senescence.
@en
type
label
E1a gene expression blocks the ...... in v-H-Ras-induced senescence.
@en
prefLabel
E1a gene expression blocks the ...... in v-H-Ras-induced senescence.
@en
P2093
P2860
P356
P1476
E1a gene expression blocks the ...... in v-H-Ras-induced senescence.
@en
P2093
Carmen Ramírez-Castillejo
Eva Galan-Moya
Jose M Rojas
Juan A Recio
Juan Guinea-Viniegra
Juan L Callejas-Valera
Natalia Martinez
Ricardo Sánchez-Prieto
Santiago Ramón y Cajal
P2860
P304
13450-13458
P356
10.1074/JBC.M709230200
P407
P577
2008-03-03T00:00:00Z