Human cytomegalovirus IE86 protein interacts with promoter-bound TATA-binding protein via a specific region distinct from the autorepression domain.
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Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86Asynchronous progression through the lytic cascade and variations in intracellular viral loads revealed by high-throughput single-cell analysis of Kaposi's sarcoma-associated herpesvirus infection.Activation of transcription of the human cytomegalovirus early UL4 promoter by the Ets transcription factor binding element.Transcriptional regulation of the human cytomegalovirus US11 early gene.Effects of human cytomegalovirus major immediate-early proteins in controlling the cell cycle and inhibiting apoptosis: studies with ts13 cellsCharacterization of the elements and proteins responsible for interferon-stimulated gene induction by human cytomegalovirus.Inhibition of cell division by the human cytomegalovirus IE86 protein: role of the p53 pathway or cyclin-dependent kinase 1/cyclin B1.Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant.Identification of positive and negative regulatory regions involved in regulating expression of the human cytomegalovirus UL94 late promoter: role of IE2-86 and cellular p53 in mediating negative regulatory function.Phosphorylation of the human cytomegalovirus 86-kilodalton immediate-early protein IE2.The human cytomegalovirus IE86 protein can block cell cycle progression after inducing transition into the S phase of permissive cells.Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: a DNA microarray analysis.Role of noncovalent SUMO binding by the human cytomegalovirus IE2 transactivator in lytic growth.Role of regulatory elements and the MAPK/ERK or p38 MAPK pathways for activation of human cytomegalovirus gene expression.The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirusInhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication.Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression.Isolation and characterization of a low-abundance splice variant from the human cytomegalovirus major immediate-early gene region.Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters.Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infectionThe autoregulatory and transactivating functions of the human cytomegalovirus IE86 protein use independent mechanisms for promoter binding.The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter.TAF-like functions of human cytomegalovirus immediate-early proteinsHuman cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment.Inhibition of IL-1beta transcription by peptides derived from the hCMV IE2 transactivator.Identification of sequence elements in the human cytomegalovirus DNA polymerase gene promoter required for activation by viral gene products.Protein-protein interactions between human cytomegalovirus IE2-580aa and pUL84 in lytically infected cells.Neutrality of the canonical NF-kappaB-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro.Cellular repressor inhibits human cytomegalovirus transcription from the UL127 promoter.Binding of cellular repressor protein or the IE2 protein to a cis-acting negative regulatory element upstream of a human cytomegalovirus early promoter.Functional interaction between the human cytomegalovirus 86-kilodalton IE2 protein and the cellular transcription factor CREB.CCAAT box-dependent activation of the TATA-less human DNA polymerase alpha promoter by the human cytomegalovirus 72-kilodalton major immediate-early proteinSite-specific binding of the human cytomegalovirus IE2 86-kilodalton protein to an early gene promoter.The human cytomegalovirus 86-kilodalton major immediate-early protein interacts physically and functionally with histone acetyltransferase P/CAF.Identification of a novel transcriptional repressor encoded by human cytomegalovirus.Viable human cytomegalovirus recombinant virus with an internal deletion of the IE2 86 gene affects late stages of viral replicationNovel immediate-early protein IE19 of human cytomegalovirus activates the origin recognition complex I promoter in a cooperative manner with IE72.Human cytomegalovirus IE2 86 and IE2 40 proteins differentially regulate UL84 protein expression posttranscriptionally in the absence of other viral gene products.Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses.
P2860
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P2860
Human cytomegalovirus IE86 protein interacts with promoter-bound TATA-binding protein via a specific region distinct from the autorepression domain.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Human cytomegalovirus IE86 pro ...... rom the autorepression domain.
@en
type
label
Human cytomegalovirus IE86 pro ...... rom the autorepression domain.
@en
prefLabel
Human cytomegalovirus IE86 pro ...... rom the autorepression domain.
@en
P2093
P2860
P1433
P1476
Human cytomegalovirus IE86 pro ...... rom the autorepression domain.
@en
P2093
P2860
P304
P407
P577
1993-12-01T00:00:00Z