The anticancer drug imatinib induces cellular autophagy.
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c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's diseaseNVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomasUnfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesAutophagy and cancerTherapeutic targeting of autophagy in neurodegenerative and infectious diseasesEGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cellsImatinib treatment causes substantial transcriptional changes in adult Schistosoma mansoni in vitro exhibiting pleiotropic effectsA novel AHI-1-BCR-ABL-DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy.New tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeuticsCardiomyocyte autophagy and cancer chemotherapy.A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation.Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST).Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxide.Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma.Perifosine induces protective autophagy and upregulation of ATG5 in human chronic myelogenous leukemia cells in vitro.Autophagy and cellular senescence mediated by Sox2 suppress malignancy of cancer cells.Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin.Autophagy collaborates with ubiquitination to downregulate oncoprotein E2A/Pbx1 in B-cell acute lymphoblastic leukemia.NVP-BEZ235 overcomes gefitinib-acquired resistance by down-regulating PI3K/AKT/mTOR phosphorylation.Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemiaCancer metabolism: strategic diversion from targeting cancer drivers to targeting cancer suppliersc-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cellsCellular prion protein (PrP(C)) and its role in stress responses.Leveraging Cancer Therapeutics for the HIV Cure Agenda: Current Status and Future DirectionsImatinib for highly chemoresistant Kaposi sarcoma in a patient with long-term HIV control: a case report and literature review.Unfolded protein response to autophagy as a promising druggable target for anticancer therapy.Prion infection impairs lysosomal degradation capacity by interfering with rab7 membrane attachment in neuronal cellsAutophagic pathways as new targets for cancer drug development.Inhibiting autophagy potentiates the anticancer activity of IFN1@/IFNα in chronic myeloid leukemia cellsCombination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancerAbelson tyrosine kinase controls phagosomal acidification required for killing of Mycobacterium tuberculosis in human macrophagesIs autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors?Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal componentsRapamycin delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmann-Sträussler-Scheinker disease.The autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model.Therapeutic targeting of autophagy in disease: biology and pharmacology.Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistanceTargeting autophagic pathways for cancer drug discoveryDiosmetin inhibits cell proliferation and induces apoptosis by regulating autophagy via the mammalian target of rapamycin pathway in hepatocellular carcinoma HepG2 cells.
P2860
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P2860
The anticancer drug imatinib induces cellular autophagy.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The anticancer drug imatinib induces cellular autophagy.
@en
type
label
The anticancer drug imatinib induces cellular autophagy.
@en
prefLabel
The anticancer drug imatinib induces cellular autophagy.
@en
P2093
P2860
P356
P1433
P1476
The anticancer drug imatinib induces cellular autophagy
@en
P2093
Elsässer HP
Yoshimori T
P2860
P2888
P304
P356
10.1038/SJ.LEU.2404606
P577
2007-03-01T00:00:00Z
P5875
P6179
1052813443