Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast.
about
The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damageProtein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonucleaseIdentification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint geneReconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNAA human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control geneHus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damageAnalysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.HRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control geneATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1The Schizosaccharomyces pombe rad3 checkpoint geneChk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpointHuman checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cellsS-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombeRACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutationThe Wee1 protein kinase regulates T14 phosphorylation of fission yeast Cdc2A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damageMad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeastThe alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNAGerminating fission yeast spores delay in G1 in response to UV irradiationFission yeast Rad26 responds to DNA damage independently of Rad3The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta.An Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model SystemCoordination of DNA damage tolerance mechanisms with cell cycle progression in fission yeast.A Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex InteractionsThe SFP1 gene product of Saccharomyces cerevisiae regulates G2/M transitions during the mitotic cell cycle and DNA-damage responseRecovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway.LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiaeRetention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damageHuman homologue of S. pombe Rad9 interacts with BCL-2/BCL-xL and promotes apoptosisPCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibitionThe Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complexRoles of Chk1 in cell biology and cancer therapyNovel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.Regulation of replication timing in fission yeast.The Schizosaccharomyces pombe checkpoint kinases Chk1 and Cds1 are important for cell survival in response to cisplatinRegulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345
P2860
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P2860
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Identification and characteriz ...... ack controls in fission yeast.
@en
type
label
Identification and characteriz ...... ack controls in fission yeast.
@en
prefLabel
Identification and characteriz ...... ack controls in fission yeast.
@en
P2093
P2860
P356
P1476
Identification and characteriz ...... ack controls in fission yeast.
@en
P2093
A R Lehmann
D J Griffiths
F al-Khodairy
K S Sheldrick
P2860
P304
P356
10.1091/MBC.5.2.147
P577
1994-02-01T00:00:00Z