Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR.
about
Cystic fibrosis transmembrane conductance regulator dysfunction and its treatmentIntegrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung diseaseHepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney diseaseCFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epitheliumToward gene therapy for cystic fibrosis using a lentivirus pseudotyped with Sendai virus envelopes.Respiratory syncytial virus engineered to express the cystic fibrosis transmembrane conductance regulator corrects the bioelectric phenotype of human cystic fibrosis airway epithelium in vitro.Nebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epithelium.A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator.Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation.Phosphorylated C/EBPβ influences a complex network involving YY1 and USF2 in lung epithelial cells.Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis.Resveratrol rescues cAMP-dependent anionic transport in the cystic fibrosis pancreatic cell line CFPAC1.The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs.Cystic Fibrosis Gene Therapy in the UK and Elsewhere.Optimization of Recombinant Adeno-Associated Virus-Mediated Expression for Large Transgenes, Using a Synthetic Promoter and Tandem Array EnhancersTranscriptional targeting in the airway using novel gene regulatory elements.Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.Relationships among CFTR expression, HCO3- secretion, and host defense may inform gene- and cell-based cystic fibrosis therapiesFront-runners for pharmacotherapeutic correction of the airway ion transport defect in cystic fibrosis.Post-transcriptional regulation of cystic fibrosis transmembrane conductance regulator expression and function by microRNAs.Non-viral vectors in cystic fibrosis gene therapy: recent developments and future prospects.Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis.Stem cell therapy for cystic fibrosis: current status and future prospects.Current status and future directions of gene and cell therapy for cystic fibrosis.Expert opinion in biological therapy: update on developments in lung gene transfer.Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung.Limitations of the murine nose in the development of nonviral airway gene transfer.Lentiviral vectors and cystic fibrosis gene therapyLatonduine Analogs Restore F508del-Cystic Fibrosis Transmembrane Conductance Regulator Trafficking through the Modulation of Poly-ADP Ribose Polymerase 3 and Poly-ADP Ribose Polymerase 16 Activity.Genetic medicines for CF: Hype versus reality.rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice.Sensitivity of chloride efflux vs. transepithelial measurements in mixed CF and normal airway epithelial cell populations.Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF modelCell surface rescue of kidney anion exchanger 1 mutants by disruption of chaperone interactions.Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicingCl transport in complemented CF bronchial epithelial cells correlates with CFTR mRNA expression levels.Cellular localization and activity of Ad-delivered GFP-CFTR in airway epithelial and tracheal cells.Amniotic mesenchymal stem cells: a new source for hepatocyte-like cells and induction of CFTR expression by coculture with cystic fibrosis airway epithelial cellsHematopoietic stem/progenitor cells express functional mitochondrial energy-dependent cystic fibrosis transmembrane conductance regulator.Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin.
P2860
Q26851242-26CED6B1-B0E4-41F6-A533-38801F3029B7Q27339615-BB82CE0C-08A7-4F22-8D15-7DCEF9F492AEQ28569447-A8389ED6-3BFE-4C02-B685-29610115A26AQ28941756-121CB54A-A623-4592-BA3E-DFC68A267E27Q33930097-E3301668-0CD9-4114-BFBE-7C20B7A457F2Q33964142-A2CE42C0-9F98-448D-856B-27224D3F743DQ34064665-F1D77548-AD7A-4C27-840E-138948333B53Q34291809-20CECC55-8E52-4BDE-8669-7044064F8037Q34479593-C02A3966-343B-4027-9765-87726B38FB0AQ34656334-657F52E3-F535-4860-8B8E-A052AC3BDEDFQ34748891-A6BD52D4-4351-44D9-9655-55DE08CCFF10Q35036202-E1965BE3-1380-4D71-B3E1-041E904949A3Q35056880-7427E2A0-3B21-4C33-B19F-A4AA184DF47BQ35641704-AB593252-7FE9-4E49-8B62-9E091883B3F2Q35821858-F9B38686-F082-41F4-A7C6-C11D4548E982Q36176927-3F820867-23A8-4A28-853E-4C03A582BB91Q36891023-96EFE311-836B-40C4-9258-A760B1FEE4FBQ36904905-5A19F74A-15DC-47D3-8F7A-D39CB9B687B9Q37158668-A7AFBC76-07D6-49FC-AE8E-10503BA3E1E2Q37297935-056BEAD6-F7DB-40D3-8750-B1F9B3D1B46FQ37526991-9E3D8F39-43C0-4E7C-9AD2-B4D26B0A22D7Q37616952-3F5E1DB9-24B3-49B6-8FA5-F5BC688FD72DQ37754873-1767A8E7-FAB3-4D01-8A12-2EC412AE642AQ37858512-3CE22C0E-4E67-4AEC-8C2A-E4C2F078B0E3Q38071683-E834E887-FE3D-49A6-985C-76DE9044C47EQ38439122-9663B0F7-8761-42F2-A783-7FFCCB1C2558Q38449399-EE984514-4CD6-4620-AF28-CF0B18223289Q38614351-D93B20E1-BD44-4D6F-B92A-DCAF0E459CA2Q38770149-C55B30B9-ACBB-40F8-94F0-427F5ECD4241Q38818339-03B312D2-1B64-411F-9391-6CB64EF782E1Q38949076-C07E9674-2021-403C-8D40-A0B17BD01CACQ39271144-627DF3CC-7B73-4E48-92C9-BBF2BD8EACC9Q39448490-9C8404AC-8E95-4989-B170-1813FC0DDF9AQ39680622-E0473501-C5AB-4C36-B4E6-BB69DCB684F8Q39877658-B17E4887-4788-415E-AA88-8D7A79F53931Q39943720-D382B4CD-439C-4F42-8098-BCE53554E76EQ40104483-B5D2FDE0-4083-4529-8CED-32470AC20973Q40792557-9DAAB975-3B2E-4664-B249-ED55AD8FE5F2Q41168425-60E97E12-990C-426C-A797-92AB2419C8A6Q41840137-A75FE3BD-974A-4FD5-A667-1090EE1E7574
P2860
Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Gene transfer of CFTR to airwa ...... can generate basolateral CFTR.
@en
type
label
Gene transfer of CFTR to airwa ...... can generate basolateral CFTR.
@en
prefLabel
Gene transfer of CFTR to airwa ...... can generate basolateral CFTR.
@en
P2093
P2860
P1476
Gene transfer of CFTR to airwa ...... can generate basolateral CFTR
@en
P2093
Arthur L Beaudet
David R Koehler
Donna J Palmer
Michael J Welsh
Philip H Karp
Sara L Farmen
P2860
P304
P356
10.1152/AJPLUNG.00049.2005
P577
2005-08-05T00:00:00Z