Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks.
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ATR suppresses endogenous DNA damage and allows completion of homologous recombination repairThe Role of PARP Inhibitors in the Treatment of Gynecologic MalignanciesVariant base excision repair proteins: contributors to genomic instabilityBLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediatesHuman CtIP promotes DNA end resectionHDAC inhibitor PCI-24781 decreases RAD51 expression and inhibits homologous recombinationInhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repairGetting Ready for the Dance: FANCJ Irons Out DNA WrinklesEnhancing tumor-targeting monoclonal antibodies therapy by PARP inhibitorsChemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promisingCompeting roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange.Phosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae.The role of DNA double-strand breaks in spontaneous homologous recombination in S. cerevisiaeBalancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Update on Poly-ADP-ribose polymerase inhibition for ovarian cancer treatmentMutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesisThe ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cellsHCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stabilityRole for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombinationTargeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzymePARP inhibition: PARP1 and beyondDifferential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks.A microhomology-mediated break-induced replication model for the origin of human copy number variation.ATR activation and replication fork restart are defective in FANCM-deficient cells.The role of RPA2 phosphorylation in homologous recombination in response to replication arrestThe homologous recombination protein RAD51D protects the genome from large deletionsSgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends.Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex.The SWI/SNF ATP-dependent nucleosome remodeler promotes resection initiation at a DNA double-strand break in yeast.DNA breaks and chromosomal aberrations arise when replication meets base excision repair.Copy number variants are produced in response to low-dose ionizing radiation in cultured cells.Deficiency of Bloom syndrome helicase activity is radiomimeticDoxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent mannerHuman DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress.More forks on the road to replication stress recoveryKu prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effectsPoly (ADP-ribose) polymerase as a novel therapeutic target in cancer.Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors.
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P2860
Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Spontaneous homologous recombi ...... nous DNA single-strand breaks.
@en
type
label
Spontaneous homologous recombi ...... nous DNA single-strand breaks.
@en
prefLabel
Spontaneous homologous recombi ...... nous DNA single-strand breaks.
@en
P2093
P2860
P1476
Spontaneous homologous recombi ...... nous DNA single-strand breaks.
@en
P2093
Helen E Bryant
Kayan M Parker
Nasrollah Saleh-Gohari
Niklas Schultz
Tobias N Cassel
P2860
P304
P356
10.1128/MCB.25.16.7158-7169.2005
P407
P577
2005-08-01T00:00:00Z