Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells.
about
A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosisBreast Cancer Metabolism and Mitochondrial Activity: The Possibility of Chemoprevention with MetforminAdipocytes: impact on tumor growth and potential sites for therapeutic interventionOncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discoveryIs cancer a metabolic disease?Disrupting P-glycoprotein function in clinical settings: what can we learn from the fundamental aspects of this transporter?Cancer: An Oxidative Crosstalk between Solid Tumor Cells and Cancer Associated FibroblastsSchistosoma mansoni Sirtuins: characterization and potential as chemotherapeutic targetsEthanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer preventionTeaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolismEndoplasmic reticulum stress and oxidative stress in cell fate decision and human disease.Ketone body utilization drives tumor growth and metastasis.Ovarian tumor-initiating cells display a flexible metabolismBioenergetic and antiapoptotic properties of mitochondria from cultured human prostate cancer cell lines PC-3, DU145 and LNCaP.Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effectAutophagy-based survival prognosis in human colorectal carcinoma.Metformin inhibits gastric cancer via the inhibition of HIF1α/PKM2 signalingIs cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolismTumor microenvironment promotes dicarboxylic acid carrier-mediated transport of succinate to fuel prostate cancer mitochondriaUsing the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone productionTumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?Noise Stress Induces an Epidermal Growth Factor Receptor/Xeroderma Pigmentosum-A Response in the Auditory Nerve.CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis.Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells.Microtargeting cancer metabolism: opening new therapeutic windows based on lipid metabolismSelf-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells.Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cellsMitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin.Creating a tumor-resistant microenvironment: cell-mediated delivery of TNFα completely prevents breast cancer tumor formation in vivo.Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis.Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer.Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexiaHypothesis: solid tumours behave as systemic metabolic dictators.Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumorsOncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration.
P2860
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P2860
Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Energy transfer in "parasitic" ...... Achilles' heel of tumor cells.
@en
type
label
Energy transfer in "parasitic" ...... Achilles' heel of tumor cells.
@en
prefLabel
Energy transfer in "parasitic" ...... Achilles' heel of tumor cells.
@en
P2093
P2860
P50
P356
P1433
P1476
Energy transfer in "parasitic" ...... Achilles' heel of tumor cells.
@en
P2093
Fabiana S Machado
Fnu Nagajyothi
Mark L Tykocinski
Richard G Pestell
P2860
P304
P356
10.4161/CC.10.24.18487
P577
2011-12-15T00:00:00Z