Two homologous phosphorylation domains differentially contribute to desensitization and internalization of the m2 muscarinic acetylcholine receptor.
about
Acidic amino acids flanking phosphorylation sites in the M2 muscarinic receptor regulate receptor phosphorylation, internalization, and interaction with arrestinsEndogenous G protein-coupled receptor kinase 6 Regulates M3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cellsDetermination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor functionProfiling of the renal kinome: a novel tool to identify protein kinases involved in angiotensin II-dependent hypertensive renal damageEndocytic regulation of alkali metal transport proteins in mammals, yeast and plants.Phosphorylation of protease-activated receptor-2 differentially regulates desensitization and internalization.G-protein coupled receptor kinases as modulators of G-protein signalling.RACK1 associates with muscarinic receptors and regulates M(2) receptor traffickingDifferential phosphorylation paradigms dictate desensitization and internalization of the N-formyl peptide receptor.The cannabinoid type-1 receptor carboxyl-terminus, more than just a tail.G-protein-coupled receptor phosphorylation: where, when and by whom.Allosteric effects of sodium ion binding on activation of the m3 muscarinic g-protein-coupled receptor.Agonist mediated internalization of M2 mAChR is beta-arrestin-dependentUnraveling a molecular determinant for clathrin-independent internalization of the M2 muscarinic acetylcholine receptor.Role of receptor-attached phosphates in binding of visual and non-visual arrestins to G protein-coupled receptors.Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalizationThe G protein-coupled receptors: pharmacogenetics and disease.The β-Arrestins: Multifunctional Regulators of G Protein-coupled ReceptorsActivation and dynamic network of the M2 muscarinic receptor.Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling.Identification of an Ascaris G protein-coupled acetylcholine receptor with atypical muscarinic pharmacologySynthetic biology with surgical precision: targeted reengineering of signaling proteins.Structural determinants of arrestin functionsBradykinin-induced internalization of the human B2 receptor requires phosphorylation of three serine and two threonine residues at its carboxyl tail.Partial phosphorylation of the N-formyl peptide receptor inhibits G protein association independent of arrestin binding.Multiple distant amino acid residues present in the serpentine region of the follitropin receptor modulate the rate of agonist-induced internalization.Arrestin binding to the M(2) muscarinic acetylcholine receptor is precluded by an inhibitory element in the third intracellular loop of the receptor.Revisiting the endocytosis of the m2 muscarinic acetylcholine receptor.Regulation of muscarinic acetylcholine receptor sequestration and function by beta-arrestin.Signaling and phosphorylation-impaired mutants of the rat follitropin receptor reveal an activation- and phosphorylation-independent but arrestin-dependent pathway for internalization.Mutation of individual serine residues in the C-terminal tail of the lutropin/choriogonadotropin receptor reveal distinct structural requirements for agonist-induced uncoupling and agonist-induced internalization.Arrestin-independent internalization of the m1, m3, and m4 subtypes of muscarinic cholinergic receptors.Internalization of the m2 muscarinic acetylcholine receptor. Arrestin-independent and -dependent pathways.GTP-binding-protein-coupled receptor kinases--two mechanistic models.Desensitization and internalization of endothelin receptor A: impact of G protein-coupled receptor kinase 2 (GRK2)-mediated phosphorylation.N-formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity.Effects of chlorpyrifos oxon on M2 muscarinic receptor internalization in different cell types.Role of receptor kinase in long-term desensitization of the cardiac muscarinic receptor-K+ channel system.Control of the cardiac muscarinic K+ channel by beta-arrestin 2.
P2860
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P2860
Two homologous phosphorylation domains differentially contribute to desensitization and internalization of the m2 muscarinic acetylcholine receptor.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Two homologous phosphorylation ...... arinic acetylcholine receptor.
@en
type
label
Two homologous phosphorylation ...... arinic acetylcholine receptor.
@en
prefLabel
Two homologous phosphorylation ...... arinic acetylcholine receptor.
@en
P2860
P356
P1476
Two homologous phosphorylation ...... arinic acetylcholine receptor.
@en
P2093
Pals-Rylaarsdam R
P2860
P304
14152-14158
P356
10.1074/JBC.272.22.14152
P407
P577
1997-05-01T00:00:00Z