5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles.
about
The cardiac ventricular 5-HT4 receptor is functional in late foetal development and is reactivated in heart failure.Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle.Conserved expression and functions of PDE4 in rodent and human heart.Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle.Spatial control of the βAR system in heart failure: the transverse tubule and beyond.Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart.Influence of phosphodiesterases and cGMP on cAMP generation and on phosphorylation of phospholamban and troponin I by 5-HT4 receptor activation in porcine left atrium.Cardiac PDEs and crosstalk between cAMP and cGMP signalling pathways in the regulation of contractility.Synergy between 5-HT4 receptor stimulation and phosphodiesterase 4 inhibition in facilitating acetylcholine release in human large intestinal circular muscle.cAMP Catalyzing Phosphodiesterases Control Cholinergic Muscular Activity But Their Inhibition Does Not Enhance 5-HT4 Receptor-Mediated Facilitation of Cholinergic Contractions in the Murine Gastrointestinal Tract.
P2860
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P2860
5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
5-HT4-elicited positive inotro ...... and human cardiac ventricles.
@en
type
label
5-HT4-elicited positive inotro ...... and human cardiac ventricles.
@en
prefLabel
5-HT4-elicited positive inotro ...... and human cardiac ventricles.
@en
P2093
P2860
P50
P356
P1476
5-HT4-elicited positive inotro ...... and human cardiac ventricles.
@en
P2093
K W Andressen
T Skomedal
P2860
P304
P356
10.1038/BJP.2008.339
P407
P577
2008-09-01T00:00:00Z