Molecular dissection of subunit interfaces in the acetylcholine receptor. Identification of residues that determine agonist selectivity.
about
Epibatidine activates muscle acetylcholine receptors with unique site selectivity.End-plate acetylcholine receptor: structure, mechanism, pharmacology, and diseaseAcetylcholine receptor delta subunit mutations underlie a fast-channel myasthenic syndrome and arthrogryposis multiplex congenitaStructure-Function Elucidation of a New -Conotoxin, Lo1a, from Conus longurionisAllosteric activation mechanism of the cys-loop receptorsImproved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation.Conotoxins targeting nicotinic acetylcholine receptors: an overviewMolecular investigations on the nicotinic acetylcholine receptor: conformational mapping and dynamic exploration using photoaffinity labeling.Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor.Electrostatic interactions regulate desensitization of the nicotinic acetylcholine receptor.Electrostatic steering at acetylcholine binding sitesNeuromuscular activity of Micrurus laticollaris (Squamata: Elapidae) venom in vitro.A mutational analysis of the acetylcholine receptor channel transmitter binding site.Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel.Properties of the human muscle nicotinic receptor, and of the slow-channel myasthenic syndrome mutant epsilonL221F, inferred from maximum likelihood fits.Contributions of the non-alpha subunit residues (loop D) to agonist binding and channel gating in the muscle nicotinic acetylcholine receptor.Mechanism of tacrine block at adult human muscle nicotinic acetylcholine receptors.Pairwise electrostatic interactions between alpha-neurotoxins and gamma, delta, and epsilon subunits of the nicotinic acetylcholine receptor.Acetylcholine and epibatidine binding to muscle acetylcholine receptors distinguish between concerted and uncoupled models.Pairwise interactions between neuronal alpha7 acetylcholine receptors and alpha-conotoxin ImI.Subunit interface selectivity of the alpha-neurotoxins for the nicotinic acetylcholine receptor.Identification of residues in the neuronal alpha7 acetylcholine receptor that confer selectivity for conotoxin ImI.Distinctions in agonist and antagonist specificity conferred by anionic residues of the nicotinic acetylcholine receptor.Epibatidine binds with unique site and state selectivity to muscle nicotinic acetylcholine receptors.Identification of residues in the adult nicotinic acetylcholine receptor that confer selectivity for curariform antagonists.Interaction of d-tubocurarine analogs with the mouse nicotinic acetylcholine receptor. Ligand orientation at the binding site.Identification of equivalent residues in the gamma, delta, and epsilon subunits of the nicotinic receptor that contribute to alpha-bungarotoxin binding.Physostigmine and galanthamine bind in the presence of agonist at the canonical and noncanonical subunit interfaces of a nicotinic acetylcholine receptor.A model of the nicotinic receptor extracellular domain based on sequence identity and residue location.Contributions of Torpedo nicotinic acetylcholine receptor gamma Trp-55 and delta Trp-57 to agonist and competitive antagonist function.Location of the polyamine binding site in the vestibule of the nicotinic acetylcholine receptor ion channel.Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism.Chimeric analysis of a neuronal nicotinic acetylcholine receptor reveals amino acids conferring sensitivity to alpha-bungarotoxin.Ligand-Gated Ion Channels.
P2860
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P2860
Molecular dissection of subunit interfaces in the acetylcholine receptor. Identification of residues that determine agonist selectivity.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Molecular dissection of subuni ...... determine agonist selectivity.
@en
type
label
Molecular dissection of subuni ...... determine agonist selectivity.
@en
prefLabel
Molecular dissection of subuni ...... determine agonist selectivity.
@en
P2860
P356
P1476
Molecular dissection of subuni ...... determine agonist selectivity.
@en
P2093
P2860
P304
25770-25777
P356
10.1074/JBC.271.42.25770
P407
P577
1996-10-01T00:00:00Z