Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition.
about
Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4Cyclin-binding motifs are essential for the function of p21CIP1Cyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivoRegulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1)The ankyrin repeat as molecular architecture for protein recognitionInteraction of D-type cyclins with a novel myb-like transcription factor, DMP1Id2 specifically alters regulation of the cell cycle by tumor suppressor proteinsRegulation of p16CDKN2 expression and its implications for cell immortalization and senescenceHypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRbRetroviral transfer of the p16INK4a cDNA inhibits C6 glioma formation in Wistar ratsRB1: a prototype tumor suppressor and an enigmaMelanoma: from mutations to medicineStructure of the cyclin-dependent kinase inhibitor p19Ink4dTargeting CDK4 and CDK6: From Discovery to TherapyA cyclin D-Cdk4 activity required for G2 phase cell cycle progression is inhibited in ultraviolet radiation-induced G2 phase delayThe INK4 family of cell cycle inhibitors in cancerDifferential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivoAccumulation of high levels of the p53 and p130 growth-suppressing proteins in cell lines stably over-expressing cyclin-dependent kinase 6 (cdk6)Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signalingGene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanismA p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanomaCyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylationIdentification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma proteinRetinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexesMammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4EFunctional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information.A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sitesGenetic replacement of cyclin D1 function in mouse development by cyclin D2.Developmental defects and tumor predisposition in Rb mutant mice.Gene methylation as a powerful biomarker for detection and screening of non-small cell lung cancer in blood.Signaling by ABL oncogenes through cyclin D1.The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27(Kip1).Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a)Establishment of irreversible growth arrest in myogenic differentiation requires the RB LXCXE-binding function.Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibilityInactivation of p16 in human mammary epithelial cells by CpG island methylationCoupled transcriptional and translational control of cyclin-dependent kinase inhibitor p18INK4c expression during myogenesis.E2F4 is exported from the nucleus in a CRM1-dependent manner.Prognostic significance of overexpressed p16INK4a in patients with cervical cancer: a meta-analysis
P2860
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P2860
Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition.
@en
type
label
Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition.
@en
prefLabel
Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition.
@en
P2093
P356
P1433
P1476
Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition.
@en
P2093
P2888
P304
P356
10.1038/375506A0
P407
P577
1995-06-01T00:00:00Z
P6179
1000987803