Identification of transactivation and repression functions of the dioxin receptor and its basic helix-loop-helix/PAS partner factor Arnt: inducible versus constitutive modes of regulation.
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Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factorsActivation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous systemMolecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.Protein-protein interaction via PAS domains: role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor-Arnt transcription factor complexThe murine Sim-2 gene product inhibits transcription by active repression and functional interferenceTwo new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesisDioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structureRtg3p, a basic helix-loop-helix/leucine zipper protein that functions in mitochondrial-induced changes in gene expression, contains independent activation domains.Differential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifsIdentification of functional domains of the aryl hydrocarbon receptorDefinition of a minimal domain of the dioxin receptor that is associated with Hsp90 and maintains wild type ligand binding affinity and specificityA novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxinDioxin induces localized, graded changes in chromatin structure: implications for Cyp1A1 gene transcriptionIdentification and functional characterization of two highly divergent aryl hydrocarbon receptors (AHR1 and AHR2) in the teleost Fundulus heteroclitus. Evidence for a novel subfamily of ligand-binding basic helix loop helix-Per-ARNT-Sim (bHLH-PAS) fThe aryl hydrocarbon receptor complex and the control of gene expressionHeat shock protein hsp90 regulates dioxin receptor function in vivo.The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor.The role of aryl hydrocarbon receptor in the pathogenesis of cardiovascular diseases.Carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in experimental models.The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcriptionThe p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activationFunctional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factorTransactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo.The role of hypoxia-inducible factors in tumorigenesis.ERK kinase inhibition stabilizes the aryl hydrocarbon receptor: implications for transcriptional activation and protein degradation.Identification of a novel domain in the aryl hydrocarbon receptor required for DNA binding.The role of mid-chain hydroxyeicosatetraenoic acids in the pathogenesis of hypertension and cardiac hypertrophy.Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt.Role of the PAS domain in regulation of dimerization and DNA binding specificity of the dioxin receptorConstitutive activation of the aromatic hydrocarbon receptor.The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice.Differential transcriptional regulation by mouse single-minded 2s.Immunohistochemical expression of HIF-1alpha in response to early myocardial ischemia.A mutation in the aryl hydrocarbon receptor (AHR) in a cultured mammalian cell line identifies a novel region of AHR that affects DNA binding.Aryl hydrocarbon receptor-mediated signal transduction.Induction of drug-metabolizing enzymes by dioxin.Transcriptional activation of cytochrome P450 genes by different classes of chemical inducers.Transcriptional activation by the mouse Ah receptor. Interplay between multiple stimulatory and inhibitory functions.Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses.
P2860
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P2860
Identification of transactivation and repression functions of the dioxin receptor and its basic helix-loop-helix/PAS partner factor Arnt: inducible versus constitutive modes of regulation.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Identification of transactivat ...... stitutive modes of regulation.
@en
type
label
Identification of transactivat ...... stitutive modes of regulation.
@en
prefLabel
Identification of transactivat ...... stitutive modes of regulation.
@en
P2093
P2860
P356
P1476
Identification of transactivat ...... stitutive modes of regulation.
@en
P2093
Gustafsson JA
Poellinger L
Whitelaw ML
P2860
P304
P356
10.1128/MCB.14.12.8343
P407
P577
1994-12-01T00:00:00Z