t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL
about
Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer PathwaysRevisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemiaThe super elongation complex (SEC) and MLL in development and disease.Structural and functional studies of FKHR-PAX3, a reciprocal fusion gene of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcomaIdentification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction.Mouse models of MLL leukemia: recapitulating the human diseasePrognostic significance of FLT3 mutational status and expression levels in MLL-AF4+ and MLL-germline acute lymphoblastic leukemia.TBP loading by AF4 through SL1 is the major rate-limiting step in MLL fusion-dependent transcription.MLL-AF4 driven leukemogenesis: what are we missing?The AF4-MLL fusion transiently augments multilineage hematopoietic engraftment but is not sufficient to initiate leukemia in cord blood CD34+ cells.
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t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL
description
2010 nî lūn-bûn
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年论文
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2010年论文
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2010年论文
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name
t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL
@en
type
label
t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL
@en
prefLabel
t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL
@en
P2093
P2860
P1433
P1476
t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL
@en
P2093
Ashish R Kumar
John H Kersey
Quanzhi Li
Thien A Sam
P2860
P304
P356
10.1016/J.LEUKRES.2010.08.011
P577
2010-09-25T00:00:00Z