Direct labelling of the human P2X7 receptor and identification of positive and negative cooperativity of binding.
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P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microgliaThe P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells.Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120.Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologueCloning and pharmacological characterization of the dog P2X7 receptor.Systemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption.Experimental characterization and mathematical modeling of P2X7 receptor channel gating.The P2X7 receptor supports both life and death in fibrogenic pancreatic stellate cellsActivation and regulation of purinergic P2X receptor channelsP2X7 receptors in neurohypophysial terminals: evidence for their role in arginine-vasopressin secretion.P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy.Structural basis for subtype-specific inhibition of the P2X7 receptor.P2X purinergic receptor ligands: recently patented compounds.The first CNS-active carborane: A novel P2X7 receptor antagonist with antidepressant activity.The microglial ATP-gated ion channel P2X7 as a CNS drug target.Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks.Natural compounds with P2X7 receptor-modulating properties.Agonist potency at P2X7 receptors is modulated by structurally diverse lipids.Nanoparticles can cause DNA damage across a cellular barrier.Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors.Mechanism of action of species-selective P2X(7) receptor antagonists.Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effectsNegative and positive allosteric modulators of the P2X(7) receptor.Unraveling subunit cooperativity in homotetrameric HCN2 channels.Tissue-nonspecific alkaline phosphatase promotes axonal growth of hippocampal neurons.A half-site multimeric enzyme achieves its cooperativity without conformational changes.Regulation of innate immunity by the nucleotide pathway in children with idiopathic nephrotic syndrome.Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors.Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors.
P2860
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P2860
Direct labelling of the human P2X7 receptor and identification of positive and negative cooperativity of binding.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Direct labelling of the human ...... tive cooperativity of binding.
@en
type
label
Direct labelling of the human ...... tive cooperativity of binding.
@en
prefLabel
Direct labelling of the human ...... tive cooperativity of binding.
@en
P2093
P2860
P356
P1476
Direct labelling of the human ...... tive cooperativity of binding.
@en
P2093
A D Michel
D S Walter
I P Chessell
J P Condreay
L J Chambers
P2860
P304
P356
10.1038/SJ.BJP.0707196
P407
P577
2007-03-05T00:00:00Z