Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor beta-induced smad-dependent transcriptional activation.
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Transforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoterInactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signalingThe transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteinsING2 as a novel mediator of transforming growth factor-beta-dependent responses in epithelial cellsRequirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signalingSmad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoNTransforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding elementCritical regulation of TGFbeta signaling by Hsp90Glucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signalingParticipation of Smad2, Smad3, and Smad4 in transforming growth factor beta (TGF-beta)-induced activation of Smad7. THE TGF-beta response element of the promoter requires functional Smad binding element and E-box sequences for transcriptional regulaIdentification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-beta actionIdentification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor betaLefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptorRole of connective tissue growth factor in the pathogenesis of diabetic nephropathyAutoregulation and heterogeneity in expression of human Cripto-1The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesisTenascin-C upregulation by transforming growth factor-beta in human dermal fibroblasts involves Smad3, Sp1, and Ets1Transcriptional control by the TGF-beta/Smad signaling systemCx43 mediates TGF-beta signaling through competitive Smads binding to microtubules.TGF-β-elicited induction of tissue inhibitor of metalloproteinases (TIMP)-3 expression in fibroblasts involves complex interplay between Smad3, p38α, and ERK1/2.Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathyDeficient Smad7 expression: a putative molecular defect in scleroderma.HILI inhibits TGF-β signaling by interacting with Hsp90 and promoting TβR degradation.Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis.Smad2 and PEA3 cooperatively regulate transcription of response gene to complement 32 in TGF-β-induced smooth muscle cell differentiation of neural crest cells.The story so far: Molecular regulation of the heme oxygenase-1 gene in renal injury.Histone H3 phosphorylation (Ser10, Ser28) and phosphoacetylation (K9S10) are differentially associated with gene expression in liver of rats treated in vivo with acute ethanolMutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathwayAortic Remodelling Is Improved by 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside Involving the Smad3 Pathway in Spontaneously Hypertensive Rats.Exogenous bone morphogenetic protein-7 reduces hepatic fibrosis in Schistosoma japonicum-infected mice via transforming growth factor-β/Smad signaling.Partial Müllerian Duct Retention in Smad4 Conditional Mutant Male MiceAn essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*.Glycated albumin activates PAI-1 transcription through Smad DNA binding sites in mesangial cells.Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix metalloproteinase-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways.Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression.MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer.Nuclear factor YY1 inhibits transforming growth factor beta- and bone morphogenetic protein-induced cell differentiationSmad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta.
P2860
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P2860
Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor beta-induced smad-dependent transcriptional activation.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Cooperative binding of Smad pr ...... nt transcriptional activation.
@en
type
label
Cooperative binding of Smad pr ...... nt transcriptional activation.
@en
prefLabel
Cooperative binding of Smad pr ...... nt transcriptional activation.
@en
P2093
P2860
P356
P1476
Cooperative binding of Smad pr ...... nt transcriptional activation.
@en
P2093
P2860
P304
P356
10.1074/JBC.274.14.9431
P407
P577
1999-04-01T00:00:00Z