Accelerated loss of islet beta cells in sucrose-fed Goto-Kakizaki rats, a genetic model of non-insulin-dependent diabetes mellitus.
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Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes.Dynamic pathology of islet endocrine cells in type 2 diabetes: β-Cell growth, death, regeneration and their clinical implicationsAugmented reduction of islet β-cell mass in Goto-Kakizaki rats fed high-fat diet and its suppression by pitavastatin treatment.Inosine monophosphate dehydrogenase: A molecular switch integrating pleiotropic GTP-dependent beta-cell functions.High glucose aggravates the detrimental effects of pancreatic stellate cells on Beta-cell functionDiabetic neuropathy--a continuing enigma.Apoptosis in the beta cells: cause or consequence of insulin secretion defect in diabetes?Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intakeBioactivity-Guided Identification of Botanical Inhibitors of KetohexokinaseIsolation and characterization of islet stellate cells in rat.Islet Stellate Cells Isolated from Fibrotic Islet of Goto-Kakizaki Rats Affect Biological Behavior of Beta-Cell.Effects on high cholesterol-fed to liver, retina, hippocampus, and Harderian gland in Goto-Kakizaki rat.Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta.Effect of fructose or sucrose feeding with different levels on oral glucose tolerance test in normal and type 2 diabetic rats.Characterization of pancreatic islets in two selectively bred mouse lines with different susceptibilities to high-fat diet-induced glucose intolerance.Experimental metabolic surgery: justification and technical aspects.Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats.Overnutrition in spiny mice (Acomys cahirinus): beta-cell expansion leading to rupture and overt diabetes on fat-rich diet and protective energy-wasting elevation in thyroid hormone on sucrose-rich diet.Intermittent high glucose enhances apoptosis in INS-1 cellsChronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats.Regulation of the susceptibility to oxidative stress by cysteine availability in pancreatic beta-cells.p53-independent induction of p21(waf1/cip1) contributes to the activation of caspases in GTP-depletion-induced apoptosis of insulin-secreting cells.Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death.Whole grain consumption has a modest effect on the development of diabetes in the Goto-Kakisaki rat.Immunohistochemical and electron-microscopic observation of beta-cells in pancreatic islets of spontaneously diabetic Goto-Kakizaki rats.Hypoglycemic action of chicken meat extract in type-2 diabetic KKAy mice and GK rats.Anatomical versus functional beta-cell mass in experimental diabetes.Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass.Quantitative histopathological assessment of retardation of islets of langerhans degeneration in rosiglitazone-dosed obese ZDF rats using combined insulin and collagens (I and III) immunohistochemistry with automated image analysis and statistical mAbnormal autoregulation and tubuloglomerular feedback in prediabetic and diabetic OLETF rats.Suppression of post-prandial hyperglycaemia by pioglitazone improved islet fibrosis and macrophage migration in the Goto-Kakizaki rat.Long-term sucrose-drinking causes increased body weight and glucose intolerance in normal male rats.Augmented beta cell loss and mitochondrial abnormalities in sucrose-fed GK rats.Nkx6.1 decline accompanies mitochondrial DNA reduction but subtle nucleoid size decrease in pancreatic islet β-cells of diabetic Goto Kakizaki rats.Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology.The dipeptidyl peptidase IV inhibitor vildagliptin suppresses development of neuropathy in diabetic rodents: Effects on peripheral sensory nerve function, structure and molecular changes.Sleeve gastrectomy, but not duodenojejunostomy, preserves total beta-cell mass in Goto-Kakizaki rats evaluated by three-dimensional optical projection tomography.
P2860
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P2860
Accelerated loss of islet beta cells in sucrose-fed Goto-Kakizaki rats, a genetic model of non-insulin-dependent diabetes mellitus.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Accelerated loss of islet beta ...... n-dependent diabetes mellitus.
@en
type
label
Accelerated loss of islet beta ...... n-dependent diabetes mellitus.
@en
prefLabel
Accelerated loss of islet beta ...... n-dependent diabetes mellitus.
@en
P2093
P2860
P1476
Accelerated loss of islet beta ...... n-dependent diabetes mellitus.
@en
P2093
P2860
P304
P356
10.1016/S0002-9440(10)65596-4
P407
P577
1998-08-01T00:00:00Z