Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy.
about
Differential induction of Leishmania donovani bi-subunit topoisomerase I-DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I.Antileishmanial activity of semisynthetic lupane triterpenoids betulin and betulinic acid derivatives: synergistic effects with miltefosineIsobenzofuranone derivatives exhibit antileishmanial effect by inhibiting type II DNA topoisomerase and inducing host response.A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitro.Discovery of safe and orally effective 4-aminoquinaldine analogues as apoptotic inducers with activity against experimental visceral leishmaniasis.The effect of 3β, 6β, 16β-trihydroxylup-20(29)-ene lupane compound isolated from Combretum leprosum Mart. on peripheral blood mononuclear cells.A Novel Spirooxindole Derivative Inhibits the Growth of Leishmania donovani Parasites both In Vitro and In Vivo by Targeting Type IB TopoisomeraseTargeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death.Drug targets in Leishmania.Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discoveryImpairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process.16alpha-Hydroxycleroda-3,13 (14)Z-dien-15,16-olide from Polyalthia longifolia: a safe and orally active antileishmanial agent.Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani.Novel Nanosized Chitosan-Betulinic Acid Against Resistant Leishmania Major and First Clinical Observation of such parasite in Kidney
P2860
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P2860
Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy.
description
2003 nî lūn-bûn
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2003年の論文
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2003年論文
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2003年論文
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name
Dihydrobetulinic acid induces ...... ns in antileishmanial therapy.
@en
type
label
Dihydrobetulinic acid induces ...... ns in antileishmanial therapy.
@en
prefLabel
Dihydrobetulinic acid induces ...... ns in antileishmanial therapy.
@en
P2093
P2860
P1433
P1476
Dihydrobetulinic acid induces ...... ons in antileishmanial therapy
@en
P2093
Agneyo Ganguly
Anindya Goswami
Arnab Roy Chowdhury
Debabani Chakraborty
Gayatri Tripathi
Hemanta K Majumder
Labanya Mandal
Monidipa Ghosh
Santu Bandyopadhyay
Sibabrata Mukhopadhyay
P2860
P407
P577
2003-01-01T00:00:00Z