Systematic functional characterization of cis-regulatory motifs in human core promoters
about
Epigenetic priors for identifying active transcription factor binding sitesTargeting the Y/CCAAT box in cancer: YB-1 (YBX1) or NF-Y?Homotypic clusters of transcription factor binding sites: A model system for understanding the physical mechanics of gene expressionComputational structural analysis: multiple proteins bound to DNACore and region-enriched networks of behaviorally regulated genes and the singing genomeDISCOVER: a feature-based discriminative method for motif search in complex genomesFunctional characterization of transcription factor motifs using cross-species comparison across large evolutionary distances.Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data.Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data.A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes.Integrating multiple evidence sources to predict transcription factor binding in the human genome.The differential disease regulomeCreating and validating cis-regulatory maps of tissue-specific gene expression regulationA computational profiling of changes in gene expression and transcription factors induced by vFLIP K13 in primary effusion lymphomaReptiles and mammals have differentially retained long conserved noncoding sequences from the amniote ancestor.Transcription factor and microRNA motif discovery: the Amadeus platform and a compendium of metazoan target sets.From DNA sequence to transcriptional behaviour: a quantitative approachcDREM: inferring dynamic combinatorial gene regulation.Evolutionary origins of transcription factor binding site clustersA widespread role of the motif environment in transcription factor binding across diverse protein familiesNew meta-analysis tools reveal common transcriptional regulatory basis for multiple determinants of behaviorSequence and chromatin determinants of cell-type-specific transcription factor bindingPRISM offers a comprehensive genomic approach to transcription factor function predictionControl of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasisNF-Y coassociates with FOS at promoters, enhancers, repetitive elements, and inactive chromatin regions, and is stereo-positioned with growth-controlling transcription factors.Module map of stem cell genes guides creation of epithelial cancer stem cellsPASTAA: identifying transcription factors associated with sets of co-regulated genes.How motif environment influences transcription factor search dynamics: Finding a needle in a haystackNF-Y and the transcriptional activation of CCAAT promoters.Lineage factors and differentiation states in lung cancer progression.Assigning roles to DNA regulatory motifs using comparative genomics.A high definition look at the NF-Y regulome reveals genome-wide associations with selected transcription factors.Predicting cell-type-specific gene expression from regions of open chromatin.NF-Y recruits Ash2L to impart H3K4 trimethylation on CCAAT promoters.Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay.Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments.Revealing global regulatory perturbations across human cancers.Ab initio identification of functionally interacting pairs of cis-regulatory elements.Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation.
P2860
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P2860
Systematic functional characterization of cis-regulatory motifs in human core promoters
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Systematic functional characterization of cis-regulatory motifs in human core promoters
@en
type
label
Systematic functional characterization of cis-regulatory motifs in human core promoters
@en
prefLabel
Systematic functional characterization of cis-regulatory motifs in human core promoters
@en
P2093
P2860
P356
P1433
P1476
Systematic functional characterization of cis-regulatory motifs in human core promoters
@en
P2093
Howard Y Chang
Saurabh Sinha
Yair Field
P2860
P304
P356
10.1101/GR.6828808
P577
2008-02-06T00:00:00Z