The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine.
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Axons amplify somatic incomplete spikes into uniform amplitudes in mouse cortical pyramidal neuronsQuinine blocks specific gap junction channel subtypesRole of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmiasThe hitchhiker's guide to the voltage-gated sodium channel galaxyProtective effects of antiarrhythmic agents against anoxic injury in CNS white matterCytoplasmic polyamines as permeant blockers and modulators of the voltage-gated sodium channel.Tetrapentylammonium block of chloramine-T and veratridine modified rat brain type IIA sodium channelsCommon molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channelsLocating the route of entry and binding sites of benzocaine and phenytoin in a bacterial voltage gated sodium channelOpioid-like actions of neuropeptide Y in rat substantia gelatinosa: Y1 suppression of inhibition and Y2 suppression of excitationExploring the structure of the voltage-gated Na+ channel by an engineered drug access pathway to the receptor site for local anesthetics.Degenerate perturbations of protein structure as the mechanism of anaesthetic action.Sodium channel selectivity filter regulates antiarrhythmic drug bindingTopology of the P segments in the sodium channel pore revealed by cysteine mutagenesisDifferences in steady-state inactivation between Na channel isoforms affect local anesthetic binding affinity.Use-dependent inhibition of Na+ currents by benzocaine homologs.Distinct local anesthetic affinities in Na+ channel subtypesFast lidocaine block of cardiac and skeletal muscle sodium channels: one site with two routes of access.Dual actions of procainamide on batrachotoxin-activated sodium channels: open channel block and prevention of inactivationDissecting lidocaine action: diethylamide and phenol mimic separate modes of lidocaine block of sodium channels from heart and skeletal muscleUse dependence of tetrodotoxin block of sodium channels: a revival of the trapped-ion mechanism.Characterization of cocaine-induced block of cardiac sodium channels.Kinetic analysis of phasic inhibition of neuronal sodium currents by lidocaine and bupivacaineA novel action of isoproterenol to inactivate a cardiac K+ current is not blocked by beta and alpha adrenergic blockers.Batrachotoxin-resistant Na+ channels derived from point mutations in transmembrane segment D4-S6Molecular mechanism of allosteric modification of voltage-dependent sodium channels by local anestheticsBlock and inactivation of sodium channels in nerve by amino acid derivatives. I. Dependence on voltage and sodium concentrationBlock and inactivation of sodium channels in nerve by amino acid derivatives. II. Dependence on temperature and drug concentrationThe effect of tetramethylammonium on single sodium channel currents.Solvent substitution as a probe of channel gating in Myxicola. Effects of D2O on kinetic properties of drugs that occlude channels.Human Blood Platelet Aggregation-inhibitory Target Sites Assumed to Involve Membrane PhospholipidsA quantitative description of QX222 blockade of sodium channels in squid axons.Effects of benzocaine on the kinetics of normal and batrachotoxin-modified Na channels in frog node of Ranvier.Theoretical characterization of ion channel blockade. Competitive binding to periodically accessible receptorsUse-dependent block of single sodium channels by lidocaine in guinea pig ventricular myocytes.Local anesthetic alteration of miniature endplate currents and endplate current fluctuationsInvestigating the size and dynamics of voltage-gated sodium channel fenestrationsMultiple modes of ryanodine receptor 2 inhibition by flecainide.Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics.Kinetic analysis of sodium channel block by internal methylene blue in pronased crayfish giant axons.
P2860
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P2860
The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine.
description
1973 nî lūn-bûn
@nan
1973年の論文
@ja
1973年論文
@yue
1973年論文
@zh-hant
1973年論文
@zh-hk
1973年論文
@zh-mo
1973年論文
@zh-tw
1973年论文
@wuu
1973年论文
@zh
1973年论文
@zh-cn
name
The inhibition of sodium curre ...... nary derivatives of lidocaine.
@en
type
label
The inhibition of sodium curre ...... nary derivatives of lidocaine.
@en
prefLabel
The inhibition of sodium curre ...... nary derivatives of lidocaine.
@en
P2860
P356
P1476
The inhibition of sodium curre ...... nary derivatives of lidocaine.
@en
P2093
Strichartz GR
P2860
P356
10.1085/JGP.62.1.37
P577
1973-07-01T00:00:00Z