Leaky scanning and reinitiation regulate BACE1 gene expression.
about
Molecular identification of NAT8 as the enzyme that acetylates cysteine S-conjugates to mercapturic acidsUpstream open reading frames: molecular switches in (patho)physiologyGene expression regulation by upstream open reading frames and human diseaseDepletion of GGA1 and GGA3 mediates postinjury elevation of BACE1Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.Biological changes associated with healthy versus pathological aging: a symposium review.Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression.Translation reinitiation relies on the interaction between eIF3a/TIF32 and progressively folded cis-acting mRNA elements preceding short uORFsRole of 5'- and 3'-untranslated regions of mRNAs in human diseases.Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process.Down-regulation of MIF by NFκB under hypoxia accelerated neuronal loss during stroke.uORFdb--a comprehensive literature database on eukaryotic uORF biology.Two novel DNA motifs are essential for BACE1 gene transcriptionA novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype.Transcriptional Regulation of TMP21 by NFAT.Regulation of translation by upstream translation initiation codons of surfactant protein A1 splice variants.Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expressionThe Alzheimer's disease beta-secretase enzyme, BACE1.Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processingThe Basic Biology of BACE1: A Key Therapeutic Target for Alzheimer's Disease.PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's diseaseMicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjectsRegulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer's disease.The Membrane-Bound Aspartyl Protease BACE1: Molecular and Functional Properties in Alzheimer's Disease and BeyondNew insights into the role of glycogen synthase kinase-3 in Alzheimer's disease.Transcriptional regulation of human USP24 gene expression by NF-kappa B.SP1 regulates a human SNAP-25 gene expression.Expression of the anti-amyloidogenic secretase ADAM10 is suppressed by its 5'-untranslated region.Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region.Translational regulation mechanisms of aquaporin-4 supramolecular organization in astrocytes.Upstream open reading frames regulate the cell cycle-dependent expression of the RNA helicase Rok1 in Saccharomyces cerevisiae.Hijacking of the AP-1 Signaling Pathway during Development of ATL.Marginal vitamin A deficiency facilitates Alzheimer's pathogenesis.BACE2 degradation mediated by the macroautophagy-lysosome pathway.Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.uORFs, reinitiation and alternative translation start sites in human mRNAs
P2860
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P2860
Leaky scanning and reinitiation regulate BACE1 gene expression.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Leaky scanning and reinitiation regulate BACE1 gene expression.
@en
Leaky scanning and reinitiation regulate BACE1 gene expression.
@nl
type
label
Leaky scanning and reinitiation regulate BACE1 gene expression.
@en
Leaky scanning and reinitiation regulate BACE1 gene expression.
@nl
prefLabel
Leaky scanning and reinitiation regulate BACE1 gene expression.
@en
Leaky scanning and reinitiation regulate BACE1 gene expression.
@nl
P2860
P1476
Leaky scanning and reinitiation regulate BACE1 gene expression.
@en
P2093
Weihui Zhou
P2860
P304
P356
10.1128/MCB.26.9.3353-3364.2006
P407
P50
P577
2006-05-01T00:00:00Z