G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment. - Wikidata - awgldk - TriplyDB

G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment.

G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment.

http://www.wikidata.org/entity/Q42351641

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BuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignment The regulation of hematopoietic stem cell populations Epigenetic modulators, modifiers and mediators in cancer aetiology and progression Chemical probes of histone lysine methyltransferases Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8 Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability.Haploinsufficiency of EHMT1 improves pattern separation and increases hippocampal cell proliferation Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine.Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression.G9a/GLP-dependent H3K9me2 patterning alters chromatin structure at CpG islands in hematopoietic progenitors Epigenetic dysregulation by nickel through repressive chromatin domain disruption.A hyperactive Mpl-based cell growth switch drives macrophage-associated erythropoiesis through an erythroid-megakaryocytic precursor.Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression, and mouse viability.Selective inhibitors of protein methyltransferases The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repression H3K9 methyltransferase G9a negatively regulates UHRF1 transcription during leukemia cell differentiation EZH2, the moderator in the discussion between methyltransferases at histone H3?Functional Crosstalk Between Lysine Methyltransferases on Histone Substrates: The Case of G9A/GLP and Polycomb Repressive Complex 2 Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a.Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping.EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors.Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells G9a, a multipotent regulator of gene expression.Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells Chromatin looping as a target for altering erythroid gene expression Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.The methyltransferase G9a regulates HoxA9-dependent transcription in AML.Epigenetic regulation of adult stem cell function.Ex vivo expansion of hematopoietic stem cells.KDM3B shows tumor-suppressive activity and transcriptionally regulates HOXA1 through retinoic acid response elements in acute myeloid leukemia.The expanding role of the Ehmt2/G9a complex in neurodevelopment.Inhibitors of Protein Methyltransferases and Demethylases.Optimizing autologous cell grafts to improve stem cell gene therapy.Hemoglobin genetics: recent contributions of GWAS and gene editing.Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells.A chemical probe toolbox for dissecting the cancer epigenome.G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration.

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P2860

G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment.

http://www.wikidata.org/entity/Q42351641

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

G9a/GLP-dependent histone H3K9 ...... stem cell lineage commitment.

@en

G9a/GLP-dependent histone H3K9 ...... stem cell lineage commitment.

@nl

type

label

G9a/GLP-dependent histone H3K9 ...... stem cell lineage commitment.

@en

G9a/GLP-dependent histone H3K9 ...... stem cell lineage commitment.

@nl

prefLabel

G9a/GLP-dependent histone H3K9 ...... stem cell lineage commitment.

@en

G9a/GLP-dependent histone H3K9 ...... stem cell lineage commitment.

@nl

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Genes & Development

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G9a/GLP-dependent histone H3K9 ...... stem cell lineage commitment.

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Beverly Torok-Storb

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Brent Wood

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Edward Choi

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George Georges

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Jerry Davison

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Keith Loeb

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Kyobi Skutt-Kakaria

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Patrick J Paddison

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Punam Malik

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Xiaoji Chen

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P2860

Complex beta-satellite repeat structures and the expansion of the zinc finger gene cluster in 19p12

A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters.

Delta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(-) cord blood cells

Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication

PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription

The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules

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2499-2511

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10.1101/GAD.200329.112

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22

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26

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2012-10-26T00:00:00Z

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232721424

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23105005

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3505820

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