Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.
about
SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreadingAdaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cellsSos-mediated activation of rac1 by p66shcEpidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase.N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domainsThe neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicityRole of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models.Biological activity of the thyroid TRK-T3 oncogene requires signalling through ShcGrowth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetryA microarray configuration to quantify expression levels and relative abundance of splice variants.Nitric oxide, oxidative stress, and p66Shc interplay in diabetic endothelial dysfunctionp66Shc as a switch in bringing about contrasting responses in cell growth: implications on cell proliferation and apoptosisShc and CEACAM1 interact to regulate the mitogenic action of insulinNon-redundant signal transduction of interleukin-6-type cytokines. The adapter protein Shc is specifically recruited to rhe oncostatin M receptorSignaling via Shc family adapter proteinsInsulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signalingCloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cellsTGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcADifferential regulation of Shc adaptor proteins in skeletal muscle, spinal cord and forebrain of aged rats with sensorimotor impairmentEssential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioningThe ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryoShcA signalling is essential for tumour progression in mouse models of human breast cancerNon-redundant role of Shc in Erk activation by cytoskeletal reorganizationCas mediates transcriptional activation of the serum response element by Src.The adaptor protein Shc integrates growth factor and ECM signaling during postnatal angiogenesis.Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivoSearch for genetic variants in the p66Shc longevity gene by PCR-single strand conformational polymorphism in patients with early-onset cardiovascular disease.Sck is expressed in endothelial cells and participates in vascular endothelial growth factor-induced signaling.Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factorsThe oxidative stress adaptor p66Shc is required for permanent embryo arrest in vitro.Cytochrome c signalosome in mitochondria.P66Shc signals to age.Lymphocyte antigen receptor signal integration and regulation by the SHC adaptor.Transcriptional repression of Kruppel like factor-2 by the adaptor protein p66shc.Protective Effects of Curcumin against Sodium Arsenite-induced Ovarian Oxidative Injury in a Mouse Model.Selective inhibition of protein kinase C β2 attenuates the adaptor P66 Shc-mediated intestinal ischemia-reperfusion injuryp66shc inhibits insulin-like growth factor-I signaling via direct binding to Src through its polyproline and Src homology 2 domains, resulting in impairment of Src kinase activation.Integration of growth factor, extracellular matrix, and retinoid signals during bronchial epithelial cell differentiation.Steroids up-regulate p66Shc longevity protein in growth regulation by inhibiting its ubiquitination
P2860
Q24290742-7376B38F-22EC-41DA-965C-D4095A663F6FQ24301574-54FBFAA9-886D-49C7-9BB6-6B3B9E8EFDF3Q24306686-2386D40B-ABF1-4193-B0ED-B3F8B4488F68Q24522441-B1EF0A25-D19E-4DA4-9327-9B5584D55CA0Q24523689-85BCBD9E-805D-48BF-8338-57204684290AQ24540169-F0A7C7E8-DAFA-4686-8073-AE65EF564072Q24596766-00112103-D00C-4C51-B949-90437F3ED6E2Q24645123-79B313EE-3641-4FA5-A510-ABB2DC16388FQ24648398-B3530E7D-221D-4923-91D4-8C6C79744AB8Q24795748-67EEC41D-62FD-420C-A86F-1EC6D4E17549Q24797945-DE90B2E2-1ACA-42F5-999F-8266D32827C4Q26830607-EDC79365-13A3-4EE8-AD16-3401C45F689BQ28084081-F8336BEA-3794-40FE-B9B6-143E694291B7Q28115837-BA500983-2F93-4BA6-9C07-56658C67787DQ28140259-B3CF9827-6DC4-47CC-8D70-57CC23E54533Q28199357-BBD9A435-FC62-487C-9382-1F31C4C3CAFEQ28291363-0251CE71-B42E-4543-87E3-ED3B752B0273Q28505581-A702E25E-C2A1-4D65-AEA6-A6E145307C5AQ28508328-A73F3EAD-D10D-46B5-9E95-7CD0F5FFE547Q28564997-377D3537-12FE-466C-85E3-712E1F9F004DQ28566249-8385514C-5406-4978-9817-C155D7FCD8F6Q28586248-6D875634-4EEF-4068-857A-BA8318441903Q28590157-8026E8BE-3B14-43DA-AABB-4E750E9B8CBBQ28590354-FAB933A7-2132-421C-B941-78678E698011Q30175350-608209FE-780E-4289-81E3-746FB4EE7204Q30422331-D7EC9947-FD07-4753-B14F-29874E85D856Q30452658-83417366-7430-499C-8912-7FF677803A6DQ33235602-AF6C8072-1542-40A8-AB3B-D602F7AB88CDQ33292515-6B85B570-070F-4AEC-86D1-23B38977CA21Q33305278-ED0E40F8-78AC-4C69-A921-3DF3F045ADCDQ33307804-0BB50E53-D51A-4207-AE29-8DE5837C9943Q33352540-515F2E7D-F5D2-41B1-9E14-9C822440D9E7Q33588755-572F3080-A273-435F-B055-07ECC156C0E7Q33589508-F460053A-0193-44B7-8C93-F6A9F342DF11Q33613299-5D1E3C0B-3B28-4355-BCD9-A5BFABA20D25Q33646638-ABB54102-04A4-4CDC-AB04-0CAD5397CFE1Q33654195-B7F21EF4-EC0F-4014-8FE1-52EF3BA8CEDDQ33747925-0E08C442-52A5-46C4-AD4D-58C18E751D8CQ33781551-7352D361-19EB-4230-874D-ABC8973BCB74Q33802622-B8E5987D-5D53-478E-9D00-DCF681E7F24D
P2860
Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Opposite effects of the p52shc ...... kinase-fos signalling pathway.
@en
Opposite effects of the p52shc ...... kinase-fos signalling pathway.
@nl
type
label
Opposite effects of the p52shc ...... kinase-fos signalling pathway.
@en
Opposite effects of the p52shc ...... kinase-fos signalling pathway.
@nl
prefLabel
Opposite effects of the p52shc ...... kinase-fos signalling pathway.
@en
Opposite effects of the p52shc ...... kinase-fos signalling pathway.
@nl
P2093
P2860
P50
P356
P1433
P1476
Opposite effects of the p52shc ...... kinase-fos signalling pathway
@en
P2093
E Migliaccio
P G Pelicci
P P Di Fiore
P2860
P304
P356
10.1093/EMBOJ/16.4.706
P407
P577
1997-02-01T00:00:00Z