The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
about
The MafA transcription factor appears to be responsible for tissue-specific expression of insulinMafB is required for islet beta cell maturationFoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start siteTranscription factor regulation of pancreatic organogenesis, differentiation and maturationMembers of the large Maf transcription family regulate insulin gene transcription in islet beta cellsTargeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.MafA is a key regulator of glucose-stimulated insulin secretion.Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans.MAFA controls genes implicated in insulin biosynthesis and secretionMafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.The Possible Mechanisms of the Impaired Insulin Secretion in Hypothyroid Rats.Transcriptional regulation of glucose sensors in pancreatic β-cells and liver: an update.GATA4 and GATA6 control mouse pancreas organogenesis.Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdx1 genesA switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cellsUpdate on the protective molecular pathways improving pancreatic beta-cell dysfunctionOn the origin of the beta cell.SIRT1 deacetylates FOXA2 and is critical for Pdx1 transcription and β-cell formation.MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cellsPreferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice.MafA and MafB regulate Pdx1 transcription through the Area II control region in pancreatic beta cells.Regulation of pancreas duodenum homeobox-1 expression by early growth response-1.Interactions between areas I and II direct pdx-1 expression specifically to islet cell types of the mature and developing pancreas.Pleiotropic Roles of PDX-1 in the PancreasSuppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c).
P2860
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P2860
The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
@en
The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
@nl
type
label
The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
@en
The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
@nl
prefLabel
The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
@en
The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
@nl
P2093
P2860
P356
P1476
The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
@en
P2093
Anna Means
Eva Henderson
Roland Stein
Susan E Samaras
Taka-Aki Matsuoka
P2860
P304
12263-12270
P356
10.1074/JBC.M210801200
P407
P577
2003-01-27T00:00:00Z