A specific function for phosphatidylinositol 3-kinase alpha (p85alpha-p110alpha) in cell survival and for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in de novo DNA synthesis of human colon carcinoma cells.
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Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexesShould individual PI3 kinase isoforms be targeted in cancer?Targeting p110gamma in gastrointestinal cancers: attack on multiple frontsStructure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and SelectivityA specific role of phosphatidylinositol 3-kinase gamma. A regulation of autonomic Ca(2)+ oscillations in cardiac cellsPhosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cellsTargeting the phosphoinositide 3-kinase pathway in cancerFish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth.Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.Genetic variations of the PI3K-AKT-mTOR pathway and clinical outcome in muscle invasive and metastatic bladder cancer patientsThe p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cellsPhosphatidylinositol 3-kinase: the oncoprotein.Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinaseA biochemical mechanism for the oncogenic potential of the p110beta catalytic subunit of phosphoinositide 3-kinase.INTRACELLULAR SIGNALING BY BILE ACIDS.Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.Characterization of a tumor-associated activating mutation of the p110β PI 3-kinase.Membrane rafts segregate pro- from anti-apoptotic insulin-like growth factor-I receptor signaling in colon carcinoma cells stimulated by members of the tumor necrosis factor superfamily.Signaling via class IA Phosphoinositide 3-kinases (PI3K) in human, breast-derived cell linesPhosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development.Class I PI3K in oncogenic cellular transformation.Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3-kinase inhibition in the human cervical cancer cell-line.Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics.Novel inhibitors of the PI3K family.New phosphatidylinositol 3-kinase inhibitors for cancer.Multiple roles for the p85α isoform in the regulation and function of PI3K signalling and receptor trafficking.Targeting the PI3K pathway for cancer therapy.Therapeutic targeting of the phosphatidylinositol 3-kinase signaling pathway: novel targeted therapies and advances in the treatment of colorectal cancer.PI3K in cancer-stroma interactions: bad in seed and ugly in soil.PI3K/AKT signaling pathway and cancer: an updated review.PI-3 kinase p110β: a therapeutic target in advanced prostate cancers.PI3King the right partner: unique interactions and signaling by p110β.Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.PIK3CA mutations in head and neck squamous cell carcinoma.Chemokine receptor 7 activates phosphoinositide-3 kinase-mediated invasive and prosurvival pathways in head and neck cancer cells independent of EGFR.The phosphatidylinositol-3 kinase pathway regulates bladder cancer cell invasion.Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation.E-cadherin downregulation sensitizes PTEN-mutant tumors to PI3Kβ silencing.Clinicopathological characteristics of PIK3CA and HBx mutations in Korean patients with hepatocellular carcinomas.
P2860
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P2860
A specific function for phosphatidylinositol 3-kinase alpha (p85alpha-p110alpha) in cell survival and for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in de novo DNA synthesis of human colon carcinoma cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
A specific function for phosph ...... f human colon carcinoma cells.
@en
A specific function for phosphatidylinositol 3-kinase alpha
@nl
type
label
A specific function for phosph ...... f human colon carcinoma cells.
@en
A specific function for phosphatidylinositol 3-kinase alpha
@nl
prefLabel
A specific function for phosph ...... f human colon carcinoma cells.
@en
A specific function for phosphatidylinositol 3-kinase alpha
@nl
P2093
P2860
P356
P1433
P1476
A specific function for phosph ...... f human colon carcinoma cells.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203871
P407
P577
2000-10-01T00:00:00Z
P5875
P6179
1015585101