A role for Fas in negative selection of thymocytes in vivo.
about
Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesisRORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cellsThe intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the gamesFrequent nuclear localization of ICAD and cytoplasmic co-expression of caspase-8 and caspase-3 in human lymphomasSeveral different cell surface molecules control negative selection of medullary thymocytesNegative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling.Interferon gamma-dependent intestinal pathology contributes to the lethality in bacterial superantigen-induced toxic shock syndromeThe role of the thymus in tolerance.The many roles of FAS receptor signaling in the immune systemThe caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytesFas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contactsFrom T to B and back again: positive feedback in systemic autoimmune disease.Cytolytic pathways in haematopoietic stem-cell transplantation.Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools.NF-κB in immunobiology.T-helper cell tolerance to ubiquitous nuclear antigensEssential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis.CD5-CK2 Signaling Modulates Erk Activation and Thymocyte Survival.The role of apoptosis in the development and function of T lymphocytes.MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells.Mutation in fas ligand impairs maturation of thymocytes bearing moderate affinity T cell receptorsNormal thymocyte negative selection in TRAIL-deficient mice.Receptor avidity and costimulation specify the intracellular Ca2+ signaling pattern in CD4(+)CD8(+) thymocytes.An essential role for c-FLIP in the efficient development of mature T lymphocytes.The use of genomewide ENU mutagenesis screens to unravel complex mammalian traits: identifying genes that regulate organ-specific and systemic autoimmunity.Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry.Neural stem cells, inflammation and NF-kappaB: basic principle of maintenance and repair or origin of brain tumours?Role of caspase-8 in thymus function.Genetic basis of altered central tolerance and autoimmune diseases: a lesson from AIRE mutations.Immune tolerance and transplantation.Alterations of the autoimmune regulator transcription factor and failure of central tolerance: APECED as a model.Acute systemic immune activation following conjunctival exposure to staphylococcal enterotoxin B.Thymocyte development in the absence of matrix metalloproteinase-9/gelatinase B.The thymic stromal cell line MTSC4 induced thymocyte apoptosis in a non-MHC-restricted manner.Role of acidic sphingomyelinase in Fas/CD95-mediated cell death.Endogenous superantigens shape response to exogenous superantigens.Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation.Systemic inflammatory response elicited by superantigen destabilizes T regulatory cells, rendering them ineffective during toxic shock syndromeBlocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor.Induction of apoptosis in murine fetal thymocytes following perinatal exposure to diethylstilbestrol.
P2860
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P2860
A role for Fas in negative selection of thymocytes in vivo.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
A role for Fas in negative selection of thymocytes in vivo.
@en
A role for Fas in negative selection of thymocytes in vivo.
@nl
type
label
A role for Fas in negative selection of thymocytes in vivo.
@en
A role for Fas in negative selection of thymocytes in vivo.
@nl
prefLabel
A role for Fas in negative selection of thymocytes in vivo.
@en
A role for Fas in negative selection of thymocytes in vivo.
@nl
P2093
P2860
P356
P1476
A role for Fas in negative selection of thymocytes in vivo.
@en
P2093
P2860
P304
P356
10.1084/JEM.187.9.1427
P407
P577
1998-05-01T00:00:00Z