Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody.
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Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing propertiesFibroblast growth factor-10 prevents H2O2-induced cell cycle arrest by regulation of G1 cyclins and cyclin dependent kinasesFunctional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.Genomic diversity of colorectal cancer: Changing landscape and emerging targetsActivation of the insulin-like growth factor-1 receptor induces resistance to epidermal growth factor receptor antagonism in head and neck squamous carcinoma cells.Metformin induces an intracellular reductive state that protects oesophageal squamous cell carcinoma cells against cisplatin but not copper-bis(thiosemicarbazones).Emerging therapies in gastrointestinal cancers.The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex.Herstatin, an autoinhibitor of the human epidermal growth factor receptor 2 tyrosine kinase, modulates epidermal growth factor signaling pathways resulting in growth arrest.Roles of autophagy in cetuximab-mediated cancer therapy against EGFR.Combination of anti-IGF-1R antibody A12 and ionizing radiation in upper respiratory tract cancers.Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor-targeted therapy with cetuximab and gefitinib.Insulin activates EGFR by stimulating its interaction with IGF-1R in low-EGFR-expressing TNBC cells.Molecular markers that predict response to colon cancer therapy.Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha.Research progress on criteria for discontinuation of EGFR inhibitor therapy.Targeting EGFR and HER-2 with cetuximab- and trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinomaCombating resistance to anti-IGFR antibody by targeting the integrin β3-Src pathway.Cetuximab reverses the Warburg effect by inhibiting HIF-1-regulated LDH-AIdentification and validation of COX-2 as a co-target for overcoming cetuximab resistance in colorectal cancer cells.Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.Acquired resistance to anti-EGFR mAb ICR62 in cancer cells is accompanied by an increased EGFR expression, HER-2/HER-3 signalling and sensitivity to pan HER blockers.Pharmacological inhibition of HSP90 and ras activity as a new strategy in the treatment of HNSCC.Metformin induces G1 cell cycle arrest and inhibits cell proliferation in nasopharyngeal carcinoma cells.Inhibition of insulin receptor isoform-A signalling restores sensitivity to gefitinib in previously de novo resistant colon cancer cells.Fibroblast growth factor-10 prevents asbestos-induced alveolar epithelial cell apoptosis by a mitogen-activated protein kinase-dependent mechanism.Growth factor mediated signaling in pancreatic pathogenesisThe farnesyl transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate.Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma.Cetuximab-mediated cellular cytotoxicity is inhibited by HLA-E membrane expression in colon cancer cells.EGF activates an inducible survival response via the RAS-> Erk-1/2 pathway to counteract interferon-alpha-mediated apoptosis in epidermoid cancer cells.Unraveling resistance to trastuzumab (Herceptin): insulin-like growth factor-I receptor, a new suspect.Panitumumab as a radiosensitizing agent in KRAS wild-type locally advanced rectal cancer.
P2860
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P2860
Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Fibroblast growth factor and i ...... receptor monoclonal antibody.
@en
Fibroblast growth factor and i ...... receptor monoclonal antibody.
@nl
type
label
Fibroblast growth factor and i ...... receptor monoclonal antibody.
@en
Fibroblast growth factor and i ...... receptor monoclonal antibody.
@nl
prefLabel
Fibroblast growth factor and i ...... receptor monoclonal antibody.
@en
Fibroblast growth factor and i ...... receptor monoclonal antibody.
@nl
P2093
P2860
P356
P1433
P1476
Fibroblast growth factor and i ...... r receptor monoclonal antibody
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204277
P407
P50
P577
2001-04-01T00:00:00Z
P5875
P6179
1034076763