Mutation of residue 33 of human equilibrative nucleoside transporters 1 and 2 alters sensitivity to inhibition of transport by dilazep and dipyridamole.
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Ethanol blocks adenosine uptake via inhibiting the nucleoside transport system in bronchial epithelial cellsMutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1Comparative genomic analysis of equilibrative nucleoside transporters suggests conserved protein structure despite limited sequence identity.Identification of yeast and human 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAr) transportersFunctional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocationEquilibrative nucleoside transporters-A review.Clearance of rapid adenosine release is regulated by nucleoside transporters and metabolism.Genomic analysis of nucleoside transporters in Diptera and functional characterization of DmENT2, a Drosophila equilibrative nucleoside transporter.Second-site suppression of a nonfunctional mutation within the Leishmania donovani inosine-guanosine transporter.Role of transmembrane domain 4 in ligand permeation by Crithidia fasciculata equilibrative nucleoside transporter 2 (CfNT2).Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1).Adenosine transport by plasma membrane monoamine transporter: reinvestigation and comparison with organic cationsTyrosine 112 is essential for organic cation transport by the plasma membrane monoamine transporterAdenosine as a signaling molecule in the retina: biochemical and developmental aspects.Molecular biology and regulation of nucleoside and nucleobase transporter proteins in eukaryotes and prokaryotes.Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets.Purine import into malaria parasites as a target for antimalarial drug development.Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy.Nucleoside transporters in chronic lymphocytic leukaemia.Nucleoside and nucleobase transporters in parasitic protozoa.Residue Ile89 in human plasma membrane monoamine transporter influences its organic cation transport activity and sensitivity to inhibition by dilazepCysteine cross-linking defines the extracellular gate for the Leishmania donovani nucleoside transporter 1.1 (LdNT1.1).Sustained adenosine exposure causes lung endothelial barrier dysfunction via nucleoside transporter-mediated signaling.Sustained adenosine exposure causes lung endothelial apoptosis: a possible contributor to cigarette smoke-induced endothelial apoptosis and lung injury.Renal nucleoside transporters: physiological and clinical implications.Synthesis and biological activity of a gemcitabine phosphoramidate prodrugConcentrative nucleoside transporters (CNTs) in epithelia: from absorption to cell signaling.The role of mitochondrial and plasma membrane nucleoside transporters in drug toxicity.An ab Initio structural model of a nucleoside permease predicts functionally important residues.Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4).Functional characterization of human equilibrative nucleoside transporter 1.Transporters that translocate nucleosides and structural similar drugs: structural requirements for substrate recognition.Biphasic increase of gap junction coupling induced by dipyridamole in the rat aortic A-10 vascular smooth muscle cell line.Molecular evolution of the equilibrative nucleoside transporter family: identification of novel family members in prokaryotes and eukaryotes.Selective Inhibition of Human Equilibrative and Concentrative Nucleoside Transporters by BCR-ABL Kinase Inhibitors: IDENTIFICATION OF KEY hENT1 AMINO ACID RESIDUES FOR INTERACTION WITH BCR-ABL KINASE INHIBITORS.Characterization of three novel members of the Arabidopsis thaliana equilibrative nucleoside transporter (ENT) familyVector-independent transmembrane transport of oligodeoxyribonucleotides involves p38 mitogen activated protein kinase phosphorylation.Cysteine-accessibility analysis of transmembrane domains 11-13 of human concentrative nucleoside transporter 3.Comparison of the interaction of uridine, cytidine, and other pyrimidine nucleoside analogues with recombinant human equilibrative nucleoside transporter 2 (hENT2) produced in Saccharomyces cerevisiae.Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.
P2860
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P2860
Mutation of residue 33 of human equilibrative nucleoside transporters 1 and 2 alters sensitivity to inhibition of transport by dilazep and dipyridamole.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Mutation of residue 33 of huma ...... t by dilazep and dipyridamole.
@en
Mutation of residue 33 of huma ...... t by dilazep and dipyridamole.
@nl
type
label
Mutation of residue 33 of huma ...... t by dilazep and dipyridamole.
@en
Mutation of residue 33 of huma ...... t by dilazep and dipyridamole.
@nl
prefLabel
Mutation of residue 33 of huma ...... t by dilazep and dipyridamole.
@en
Mutation of residue 33 of huma ...... t by dilazep and dipyridamole.
@nl
P2093
P2860
P356
P1476
Mutation of residue 33 of huma ...... t by dilazep and dipyridamole.
@en
P2093
Amy M L Ng
Carol E Cass
Frank Visser
James D Young
Mark F Vickers
P2860
P304
P356
10.1074/JBC.M105324200
P407
P577
2001-10-31T00:00:00Z