Evaluation of the pharmacokinetics, biotransformation and hepatic transporter effects of troglitazone in mice with humanized livers.

Evaluation of the pharmacokinetics, biotransformation and hepatic transporter effects of troglitazone in mice with humanized livers.

Item
http://www.wikidata.org/entity/Q44160577
Assessment of chimeric mice with humanized livers in new drug development: generation of pharmacokinetics, metabolism and toxicity data for selecting the final candidate compound.Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse.Current therapies and future possibilities for drug development against liver-stage malaria.A mouse with humanized liver as an animal model for predicting drug effects and for studying hepatic viral infection: where to next?Chimeric mice transplanted with human hepatocytes as a model for prediction of human drug metabolism and pharmacokinetics.Chimeric rodents with humanized liver: bridging the preclinical/clinical trial gap in ADME/toxicity studies.Current status of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver.Endogenous and xenobiotic metabolite profiling of liver extracts from SCID and chimeric humanized mice following repeated oral administration of troglitazone.Pharmacokinetics and metabolism of midazolam in chimeric mice with humanised livers.The application of a new microfluidic device for the simultaneous identification and quantitation of midazolam metabolites obtained from a single micro-litre of chimeric mice blood.
P2860

Evaluation of the pharmacokinetics, biotransformation and hepatic transporter effects of troglitazone in mice with humanized livers.

Item
http://www.wikidata.org/entity/Q44160577
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Evaluation of the pharmacokine ...... in mice with humanized livers.
@en
Evaluation of the pharmacokine ...... in mice with humanized livers.
@nl
type
label
Evaluation of the pharmacokine ...... in mice with humanized livers.
@en
Evaluation of the pharmacokine ...... in mice with humanized livers.
@nl
prefLabel
Evaluation of the pharmacokine ...... in mice with humanized livers.
@en
Evaluation of the pharmacokine ...... in mice with humanized livers.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Evaluation of the pharmacokine ...... in mice with humanized livers.
@en
P2093
P2860
P304
P31
P356
10.3109/00498254.2011.640716
P407
P433
P478
P50
P577
P698