Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei.

Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei.

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http://www.wikidata.org/entity/Q44320741
Identification of novel genes involved in long-chain n-alkane degradation by Acinetobacter sp. strain DSM 17874.Crucial factor for increasing the conjugation frequency in Streptomyces netropsis SD-07 and other strains.Biosynthesis and pathway engineering of antifungal polyene macrolides in actinomycetes.Initiation of polyene macrolide biosynthesis: interplay between polyketide synthase domains and modules as revealed via domain swapping, mutagenesis, and heterologous complementation.New nystatin-related antifungal polyene macrolides with altered polyol region generated via biosynthetic engineering of Streptomyces noursei.Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin.Chemical diversity of polyene macrolides produced by Streptomyces noursei ATCC 11455 and recombinant strain ERD44 with genetically altered polyketide synthase NysC.In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis.Characterization of the P450 monooxygenase NysL, responsible for C-10 hydroxylation during biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.Engineered polyketides: Synergy between protein and host level engineering.New Alpiniamides From sp. IB2014/011-12 Assembled by an Unusual Hybrid Non-ribosomal Peptide Synthetase -AT Polyketide Synthase Enzyme
P2860

Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei.

Item
http://www.wikidata.org/entity/Q44320741
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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@zh-hans
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@zh-my
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2003年學術文章
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name
Site-specific mutagenesis and ...... hesis in Streptomyces noursei.
@en
Site-specific mutagenesis and ...... hesis in Streptomyces noursei.
@nl
type
label
Site-specific mutagenesis and ...... hesis in Streptomyces noursei.
@en
Site-specific mutagenesis and ...... hesis in Streptomyces noursei.
@nl
prefLabel
Site-specific mutagenesis and ...... hesis in Streptomyces noursei.
@en
Site-specific mutagenesis and ...... hesis in Streptomyces noursei.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Site-specific mutagenesis and ...... thesis in Streptomyces noursei
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698