Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization.
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C-terminal phosphorylation controls the stability and function of p27kip114-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensationNext-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategyActivation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesRSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.Transforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor proteinCell-permeable Carboxyl-terminal p27Kip1 Peptide Exhibits Anti-tumor Activity by Inhibiting Pim-1 KinaseLocalization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its functionCdc6 protein activates p27KIP1-bound Cdk2 protein only after the bound p27 protein undergoes C-terminal phosphorylationMolecular dynamics and in vitro analysis of Connexin43: A new 14-3-3 mode-1 interacting proteinERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functionsp27Kip1 localization depends on the tumor suppressor protein tuberin.Two p90 ribosomal S6 kinase isoforms are involved in the regulation of mitotic and meiotic arrest in Artemia.Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.Ribosomal S6 kinase regulates ischemia-induced progenitor cell proliferation in the adult mouse hippocampus.Patterns of p57Kip2 expression in embryonic rat brain suggest roles in progenitor cell cycle exit and neuronal differentiationInducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism.Treatment of a human papillomavirus type 31b-positive cell line with benzo[a]pyrene increases viral titer through activation of the Erk1/2 signaling pathwayp90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors.cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinomaMechanism of p27 upregulation induced by downregulation of cathepsin B and uPAR in gliomamicroRNA-103/107 Family Regulates Multiple Epithelial Stem Cell CharacteristicsDynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes.p27kip1: a target for tumor therapies?Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitorsRibosomal S6 kinase as a mediator of keratinocyte growth factor-induced activation of Akt in epithelial cells.Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation.A crosstalk imbalance between p27(Kip1) and its interacting molecules enhances breast carcinogenesisThe PDK1-Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning.Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare MutationsC-terminal binding: an expanded repertoire and function of 14-3-3 proteins.14-3-3ε plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycleRan-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transportRole of dual specificity tyrosine-phosphorylation-regulated kinase 1B (Dyrk1B) in S-phase entry of HPV E7 expressing cells from quiescenceMutant AKT1-E17K is oncogenic in lung epithelial cellsLoss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression
P2860
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P2860
Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
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2003年學術文章
@zh-hant
name
Phosphorylation of p27Kip1 at ...... and cytoplasmic localization.
@en
Phosphorylation of p27Kip1 at ...... and cytoplasmic localization.
@nl
type
label
Phosphorylation of p27Kip1 at ...... and cytoplasmic localization.
@en
Phosphorylation of p27Kip1 at ...... and cytoplasmic localization.
@nl
prefLabel
Phosphorylation of p27Kip1 at ...... and cytoplasmic localization.
@en
Phosphorylation of p27Kip1 at ...... and cytoplasmic localization.
@nl
P2093
P2860
P356
P1476
Phosphorylation of p27Kip1 at ...... and cytoplasmic localization.
@en
P2093
Naoya Fujita
Saori Sato
Takashi Tsuruo
P2860
P304
49254-49260
P356
10.1074/JBC.M306614200
P407
P577
2003-09-22T00:00:00Z