Homologous DNA Pairing and Strand Exchange - Wikidata - awgldk - TriplyDB

Homologous DNA Pairing and Strand Exchange

Homologous DNA Pairing and Strand Exchange

http://www.wikidata.org/entity/Q45314242

about

Presynaptic phase of homologous DNA pairing and strand exchange D-loop formation mediated by PALB2; BRCA2 and RAD51 CX3 complex formation CX3 complex binds D-loop structures

P361

HDR through Homologous Recombination (HRR)

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Q45314244-DD7BBAA2-706B-4534-A2F4-133B966A2188 Q50287365-18F31BC4-B7E9-40CE-9E13-05580528C3DF Q50287366-DD84958F-DF79-4476-AA14-A3C107751779 Q50287367-F0CB9013-1A1B-40C6-AA41-61CE6C175CA7

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Q45314241-5AF0C1E9-32BB-43CB-8796-485465EFA71E

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Homologous DNA Pairing and Strand Exchange

http://www.wikidata.org/entity/Q45314242

description

An instance of the biological ...... trand Exchange in Homo sapiens

@en

name

Homologous DNA Pairing and Strand Exchange

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type

label

Homologous DNA Pairing and Strand Exchange

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prefLabel

Homologous DNA Pairing and Strand Exchange

@en

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Q45314242-71AA23BE-7F7E-4AA1-9D1D-DC0F7BE4E97E

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Q45314242-BEAAA2FB-B17C-4FC2-B047-1B30B988B0EF

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Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.

Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

The DNA Damage Response: Making It Safe to Play with Knives

Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination

Rad51 recombinase and recombination mediators.

Promotion of homologous recombination and genomic stability by RAD51AP1 via RAD51 recombinase enhancement.

PALB2 links BRCA1 and BRCA2 in the DNA-damage response.

Human Rad51 protein can form homologous joints in the absence of net strand exchange.

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reactome:R-HSA-5693579

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biological pathway

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HDR through Homologous Recombination (HRR)

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R-HSA-5693579

http://www.w3.org/2001/XMLSchema#string

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Presynaptic phase of homologous DNA pairing and strand exchange

D-loop formation mediated by PALB2; BRCA2 and RAD51

CX3 complex formation

CX3 complex binds D-loop structures

P703