Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism.
about
Irinotecan, a key chemotherapeutic drug for metastatic colorectal cancerDosing Recommendations for Concomitant Medications During 3D Anti-HCV TherapySimultaneous assessment of uptake and metabolism in rat hepatocytes: a comprehensive mechanistic modelImpact of OATP transporters on pharmacokinetics.The effect of SLCO1B1 polymorphism on repaglinide pharmacokinetics persists over a wide dose range.Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption.Transporter-mediated drug-drug interactions with oral antidiabetic drugs.In vitro and in vivo approaches to characterize transporter-mediated disposition in drug discovery.Prediction of pharmacokinetics and drug-drug interactions when hepatic transporters are involved.Comparative Bioavailability and Tolerability of a Single 2-mg Dose of 2 Repaglinide Tablet Formulations in Fasting, Healthy Chinese Male Volunteers: An Open-Label, Randomized-Sequence, 2-Period Crossover Study.Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS).Progress in Prediction and Interpretation of Clinically Relevant Metabolic Drug-Drug Interactions: a Minireview Illustrating Recent Developments and Current Opportunities.Effects of Fluvastatin on the Pharmacokinetics of Repaglinide: Possible Role of CYP3A4 and P-glycoprotein Inhibition by Fluvastatin.The influence of oral antidiabetic drugs on cellular drug uptake mediated by hepatic OATP family members.PharmGKB very important pharmacogene: SLCO1B1.Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation.Severe hypoglycaemia from repaglinide-brotizolam drug interaction: a case report and literature review.The pregnane X receptor agonist St John's Wort has no effects on the pharmacokinetics and pharmacodynamics of repaglinide.Effects of diltiazem on pharmacokinetics of tacrolimus in relation to CYP3A5 genotype status in renal recipients: from retrospective to prospective.Gemfibrozil Is a Strong Inactivator of CYP2C8 in Very Small Multiple DosesMechanism-Based Inactivation of CYP2C8 by Gemfibrozil Occurs Rapidly in Humans
P2860
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P2860
Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Effects of gemfibrozil and ato ...... ation to SLCO1B1 polymorphism.
@en
Effects of gemfibrozil and ato ...... ation to SLCO1B1 polymorphism.
@nl
type
label
Effects of gemfibrozil and ato ...... ation to SLCO1B1 polymorphism.
@en
Effects of gemfibrozil and ato ...... ation to SLCO1B1 polymorphism.
@nl
prefLabel
Effects of gemfibrozil and ato ...... ation to SLCO1B1 polymorphism.
@en
Effects of gemfibrozil and ato ...... ation to SLCO1B1 polymorphism.
@nl
P2093
P2860
P356
P1476
Effects of gemfibrozil and ato ...... ation to SLCO1B1 polymorphism.
@en
P2093
A Kalliokoski
J T Backman
K J Kurkinen
P2860
P304
P356
10.1038/CLPT.2008.74
P407
P577
2008-10-01T00:00:00Z