Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila.
about
Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2Current view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2Modeling glial contributions to seizures and epileptogenesis: cation-chloride cotransporters in Drosophila melanogasterDrosophila sodium channel mutations: Contributions to seizure-susceptibilityMutations in SLC12A5 in epilepsy of infancy with migrating focal seizures.A variant of KCC2 from patients with febrile seizures impairs neuronal Cl- extrusion and dendritic spine formationThe RCC1 domain of protein associated with Myc (PAM) interacts with and regulates KCC2A Drosophila systems model of pentylenetetrazole induced locomotor plasticity responsive to antiepileptic drugs.Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain.Structural and functional evaluation of C. elegans filamins FLN-1 and FLN-2.Functional genomics in Drosophila models of human disease.A novel N-terminal isoform of the neuron-specific K-Cl cotransporter KCC2.The role and the mechanism of gamma-aminobutyric acid during central nervous system developmentRole of an apical K,Cl cotransporter in urine formation by renal tubules of the yellow fever mosquito (Aedes aegypti).Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophreniaA novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and diseaseTyrosine phosphorylation regulates the membrane trafficking of the potassium chloride co-transporter KCC2.From bench to drug: human seizure modeling using DrosophilaKinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.Emerging epilepsy models: insights from mice, flies, worms and fish.Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy.Drosophila as a model for intractable epilepsy: gilgamesh suppresses seizures in para(bss1) heterozygote flies.Seizure and epilepsy: studies of seizure disorders in Drosophila.K-Cl cotransporter KCC2--a moonlighting protein in excitatory and inhibitory synapse development and function.The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters.The Drosophila blood-brain barrier: development and function of a glial endothelium.Molecular cloning and biochemical characterization of two cation chloride cotransporter subfamily members of Hydra vulgaris.Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy.WNK Kinases in Development and Disease.Drosophila glia use a conserved cotransporter mechanism to regulate extracellular volumeGenome-wide screen for modifiers of Na (+) /K (+) ATPase alleles identifies critical genetic loci.Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: development of a highly selective and more potent in vitro probe.Evolution of the cation chloride cotransporter family: ancient origins, gene losses, and subfunctionalization through duplication.Prevalence of Epilepsy among Cataract Patients.The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition.
P2860
Q26829362-DF8087F7-034D-4767-85A9-82F887FA3D90Q27004031-B1DB879B-AD23-4596-9355-E0C11C085D6AQ27321234-EF3B1500-1326-456B-B4E9-9DA25EAAA95AQ28082964-6845CFBC-2214-4697-931A-F9F9BAF10F2AQ28116136-AD9FCBB9-1296-41BB-AA9D-7451E0C77959Q28116504-E043AD12-E71D-441B-A060-FD67A63284A0Q28511194-5CE03192-0D49-491D-B23B-D9FCF522B693Q30486566-EBD0AAC5-6456-4B98-8A22-A8B5C54A1450Q33417208-BD48C531-EF37-4EA3-8689-721544C07183Q33628412-352795D7-094C-4F49-9109-7742C7A57BA7Q33974916-6FF42E09-28CD-4289-88BA-54AF3F173D2FQ34390078-ECBC0444-6E96-4195-8B6D-FCD2284670BCQ34666624-8E32D5AD-676C-4FBE-BF8F-59E9C027D125Q34781484-B83FFA66-B5EF-4254-AD59-7772B26DDD45Q35543406-1203747D-15C6-4FE0-844D-B894EE828512Q36145999-BB1B7708-FC35-479B-BBC2-64CBA274DB0BQ36206004-0D5D7036-2A14-4B7C-8AA1-95F823AF7BD5Q36485579-9BBFAF81-323C-48A0-B1E4-4F5EC835A81CQ36496588-863D90C0-B352-4B8A-BBB5-808397255989Q36598125-D2DDD898-4F1F-4FE3-BF60-9BDD83E2AFF2Q36757300-797C3505-5635-4BC5-83C1-A56408B63F97Q37013527-FFF60063-8B6C-4A26-AA95-6EB01C8C61B9Q37079548-D5F40D09-8DC3-44F3-9841-ECD9D09C2F26Q37929935-4365B2C9-3B50-4D79-AA02-B3D88CABB7DCQ38218526-533FB77A-E348-45AB-BDFA-88C323A51495Q38230038-85FB41FC-2167-4DD7-9EFB-09548859515BQ38276387-913C2AF4-8BCC-4BD3-9555-D55D2165B150Q38702377-B18B4D65-0E6B-492F-B3C1-8421BDA534B5Q38984830-221CE686-F7DB-437E-9078-27FD9DA16E3AQ39150531-8B0D5E2A-9FD5-415A-A1C0-3E9D57AE84F9Q41260120-F70FA2CC-7676-45FB-8E1B-5D268807260FQ41726164-139FE868-7E00-4E66-A48B-7A3661CFE6CDQ42224632-7A69D537-1A04-4E5E-B808-B14005584D04Q42449855-FAED0FB3-041F-4EB1-A06B-D9C27DFE118BQ43064770-D458D1B3-CA42-475E-9185-B3AE2D0DDBF7Q50312624-C4337A16-7B29-469D-A9EA-C42DCFBCC4D6
P2860
Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Mutations in the K+/Cl- cotran ...... susceptibility in Drosophila.
@en
Mutations in the K+/Cl- cotransporter gene kazachoc
@nl
type
label
Mutations in the K+/Cl- cotran ...... susceptibility in Drosophila.
@en
Mutations in the K+/Cl- cotransporter gene kazachoc
@nl
prefLabel
Mutations in the K+/Cl- cotran ...... susceptibility in Drosophila.
@en
Mutations in the K+/Cl- cotransporter gene kazachoc
@nl
P2093
P1476
Mutations in the K+/Cl- cotran ...... e susceptibility in Drosophila
@en
P2093
Daria S Hekmat-Scafe
Mark A Tanouye
Miriam Y Lundy
Rakhee Ranga
P304
P356
10.1523/JNEUROSCI.4998-05.2006
P407
P577
2006-08-01T00:00:00Z