An orientation-dependent hydrogen bonding potential improves prediction of specificity and structure for proteins and protein-protein complexes.
about
Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion holeThe roles of entropy and kinetics in structure predictionDesign of a Novel Globular Protein Fold with Atomic-Level AccuracyHigh-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein designImproved prediction of protein side-chain conformations with SCWRL4The RosettaDock server for local protein-protein dockingModulation of calcium oxalate dihydrate growth by selective crystal-face binding of phosphorylated osteopontin and polyaspartate peptide showing occlusion by sectoral (compositional) zoningBalancing solvation and intramolecular interactions: toward a consistent generalized Born force fieldPredicting continuous local structure and the effect of its substitution for secondary structure in fragment-free protein structure predictionThe discovery of the alpha-helix and beta-sheet, the principal structural features of proteinsRosettaDesign server for protein designEstimates of statistical significance for comparison of individual positions in multiple sequence alignmentsProtein-DNA binding specificity predictions with structural modelsAn Integrated Framework Advancing Membrane Protein Modeling and DesignStructure-based Protocol for Identifying Mutations that Enhance Protein–Protein Binding AffinitiesHigh-resolution design of a protein loopThe crystal structure of progesterone 5beta-reductase from Digitalis lanata defines a novel class of short chain dehydrogenases/reductasesTesting Geometrical Discrimination within an Enzyme Active Site: Constrained Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion HoleA Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its FamilyComputational design of a symmetric homodimer using -strand assemblyMutations in NOTCH1 cause Adams-Oliver syndromeBiocontainment of genetically modified organisms by synthetic protein designProtein design using continuous rotamersProbabilistic prediction of contacts in protein-ligand complexesThe molecular basis of conformational instability of the ecdysone receptor DNA binding domain studied by in silico and in vitro experimentsComputational Design of Hypothetical New Peptides Based on a Cyclotide Scaffold as HIV gp120 InhibitorCombined covalent-electrostatic model of hydrogen bonding improves structure prediction with RosettaQuantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognitionMulti-constraint computational design suggests that native sequences of germline antibody H3 loops are nearly optimal for conformational flexibilityScientific benchmarks for guiding macromolecular energy function improvementA simple model of backbone flexibility improves modeling of side-chain conformational variabilityPrediction of mutational tolerance in HIV-1 protease and reverse transcriptase using flexible backbone protein designRosettaBackrub--a web server for flexible backbone protein structure modeling and designBackrub-like backbone simulation recapitulates natural protein conformational variability and improves mutant side-chain predictionDesign of multi-specificity in protein interfacesA Ras-induced conformational switch in the Ras activator Son of sevenlessRational design of intercellular adhesion molecule-1 (ICAM-1) variants for antagonizing integrin lymphocyte function-associated antigen-1-dependent adhesionA new hydrogen-bonding potential for the design of protein-RNA interactions predicts specific contacts and discriminates decoysClose agreement between the orientation dependence of hydrogen bonds observed in protein structures and quantum mechanical calculationsComputational protein design: the Proteus software and selected applications.
P2860
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P2860
An orientation-dependent hydrogen bonding potential improves prediction of specificity and structure for proteins and protein-protein complexes.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
An orientation-dependent hydro ...... and protein-protein complexes.
@en
An orientation-dependent hydro ...... and protein-protein complexes.
@nl
type
label
An orientation-dependent hydro ...... and protein-protein complexes.
@en
An orientation-dependent hydro ...... and protein-protein complexes.
@nl
prefLabel
An orientation-dependent hydro ...... and protein-protein complexes.
@en
An orientation-dependent hydro ...... and protein-protein complexes.
@nl
P1476
An orientation-dependent hydro ...... and protein-protein complexes.
@en
P2093
Alexandre V Morozov
P304
P356
10.1016/S0022-2836(03)00021-4
P407
P577
2003-02-01T00:00:00Z