about
Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium BeggiatoaAnion transport in heartPotentiation of ΔF508- and G551D-CFTR-Mediated Cl- Current by Novel HydroxypyrazolinesCurcumin and genistein: the combined effects on disease-associated CFTR mutants and their clinical implicationsNovel pharmacologic therapies for cystic fibrosisNon-specific activation of the epithelial sodium channel by the CFTR chloride channelDirect effects of 9-anthracene compounds on cystic fibrosis transmembrane conductance regulator gating.Cystic fibrosis transmembrane conductance regulator protein repair as a therapeutic strategy in cystic fibrosisFast manipulation of cellular cAMP level by light in vivo.Effect of genistein on native epithelial tissue from normal individuals and CF patients and on ion channels expressed in Xenopus oocytesPotent stimulation and inhibition of the CFTR Cl(-) current by phloxine B.Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.Cardiac Na+-Ca2+ exchanger current induced by tyrphostin tyrosine kinase inhibitors.Emerging drug treatments for cystic fibrosis.Resveratrol ameliorates abnormalities of fluid and electrolyte secretion in a hypoxia-Induced model of acquired CFTR deficiencyPharmacological approaches to correcting the ion transport defect in cystic fibrosis.Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoproteinG551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit distinct gating defectsActions of genistein on cystic fibrosis transmembrane conductance regulator channel gating. Evidence for two binding sites with opposite effects.Noncatalytic inhibition of cyclic nucleotide-gated channels by tyrosine kinase induced by genistein.Dual effects of ADP and adenylylimidodiphosphate on CFTR channel kinetics show binding to two different nucleotide binding sites.Natural Compounds as Therapeutic Agents in the Treatment Cystic FibrosisFront-runners for pharmacotherapeutic correction of the airway ion transport defect in cystic fibrosis.Molecular modeling of the heterodimer of human CFTR's nucleotide-binding domains using a protein-protein docking approachDirect inhibition of the pacemaker (If) current in rabbit sinoatrial node cells by genistein.CFTR pharmacology.Protein kinase-independent activation of CFTR by phosphatidylinositol phosphates.A quantitative description of the activation and inhibition of CFTR by potentiators: Genistein.Two mechanisms of genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in murine cell line.Inhibition by genistein of the hyperpolarization-activated cation current in porcine sino-atrial node cells.Differential activation of the HCO(3)(-) conductance through the cystic fibrosis transmembrane conductance regulator anion channel by genistein and forskolin in murine duodenum.Activation of the cystic fibrosis transmembrane conductance regulator by the flavonoid quercetin: potential use as a biomarker of ΔF508 cystic fibrosis transmembrane conductance regulator rescue.Curcumin and genistein additively potentiate G551D-CFTR.Genistein stimulates electrogenic Cl- secretion via phosphodiesterase modulation in the mouse jejunum.Mechanistic insights in light-induced cAMP production by photoactivated adenylyl cyclase alpha (PACalpha).Genistein stimulates electrogenic Cl(-) secretion in mouse jejunum.Activation of cystic fibrosis transmembrane conductance regulator in rat epididymal epithelium by genistein.Role of protein phosphatases in the activation of CFTR (ABCC7) by genistein and bromotetramisole.Phloxine B interacts with the cystic fibrosis transmembrane conductance regulator at multiple sites to modulate channel activity.Genistein improves regulatory interactions between G551D-cystic fibrosis transmembrane conductance regulator and the epithelial sodium channel in Xenopus oocytes.
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Direct action of genistein on CFTR.
@en
Direct action of genistein on CFTR.
@nl
type
label
Direct action of genistein on CFTR.
@en
Direct action of genistein on CFTR.
@nl
prefLabel
Direct action of genistein on CFTR.
@en
Direct action of genistein on CFTR.
@nl
P2093
P356
P1433
P1476
Direct action of genistein on CFTR.
@en
P2093
F Weinreich
J R Riordan
P2888
P304
P356
10.1007/S004240050424
P50
P577
1997-08-01T00:00:00Z