Molecular determinants of anion selectivity in the cystic fibrosis transmembrane conductance regulator chloride channel pore.
about
Mechanisms of the noxious inflammatory cycle in cystic fibrosisRelationship between anion binding and anion permeability revealed by mutagenesis within the cystic fibrosis transmembrane conductance regulator chloride channel poreDeterminants of anion permeation in the second transmembrane domain of the mouse bestrophin-2 chloride channel.Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation.CFTR: a cysteine at position 338 in TM6 senses a positive electrostatic potential in the pore.Ion channel associated diseases: overview of molecular mechanismsModulation of CFTR gating by permeant ions.Full-open and closed CFTR channels, with lateral tunnels from the cytoplasm and an alternative position of the F508 region, as revealed by molecular dynamics.Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel.Insight in eukaryotic ABC transporter function by mutation analysis.Voltage-dependent gating of the cystic fibrosis transmembrane conductance regulator Cl- channel.CFTR: covalent and noncovalent modification suggests a role for fixed charges in anion conduction.The CFTR ion channel: gating, regulation, and anion permeationLong-range coupling between the extracellular gates and the intracellular ATP binding domains of multidrug resistance protein pumps and cystic fibrosis transmembrane conductance regulator channelsMutations at arginine 352 alter the pore architecture of CFTR.Cystic fibrosis transmembrane conductance regulator (ABCC7) structureFunctional architecture of the CFTR chloride channel.Structural Changes Fundamental to Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Pore.Architecture and functional properties of the CFTR channel pore.Interactions between permeation and gating in the TMEM16B/anoctamin2 calcium-activated chloride channel.Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore.Domain interactions in the yeast ATP binding cassette transporter Ycf1p: intragenic suppressor analysis of mutations in the nucleotide binding domainsDirect comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore.Coupled movement of permeant and blocking ions in the CFTR chloride channel pore.Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): CLOSED AND OPEN STATE CHANNEL MODELS.Stable dimeric assembly of the second membrane-spanning domain of CFTR (cystic fibrosis transmembrane conductance regulator) reconstitutes a chloride-selective pore.Relative contribution of different transmembrane segments to the CFTR chloride channel pore.Mechanism of lonidamine inhibition of the CFTR chloride channel.Identification of a region of strong discrimination in the pore of CFTR.Molecular determinants and role of an anion binding site in the external mouth of the CFTR chloride channel pore.Extent of the selectivity filter conferred by the sixth transmembrane region in the CFTR chloride channel pore.Inhibition of CFTR channels by a peptide toxin of scorpion venom.Destabilization of the transmembrane domain induces misfolding in a phenotypic mutant of cystic fibrosis transmembrane conductance regulator.A combined analysis of the cystic fibrosis transmembrane conductance regulator: implications for structure and disease models.Location of a permeant anion binding site in the cystic fibrosis transmembrane conductance regulator chloride channel pore.Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel.Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant.Structural mechanisms of CFTR function and dysfunction.The Importance of Dehydration in Determining Ion Transport in Narrow Pores
P2860
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P2860
Molecular determinants of anion selectivity in the cystic fibrosis transmembrane conductance regulator chloride channel pore.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Molecular determinants of anio ...... gulator chloride channel pore.
@ast
Molecular determinants of anio ...... gulator chloride channel pore.
@en
Molecular determinants of anio ...... gulator chloride channel pore.
@nl
type
label
Molecular determinants of anio ...... gulator chloride channel pore.
@ast
Molecular determinants of anio ...... gulator chloride channel pore.
@en
Molecular determinants of anio ...... gulator chloride channel pore.
@nl
prefLabel
Molecular determinants of anio ...... gulator chloride channel pore.
@ast
Molecular determinants of anio ...... gulator chloride channel pore.
@en
Molecular determinants of anio ...... gulator chloride channel pore.
@nl
P2093
P2860
P1433
P1476
Molecular determinants of anio ...... gulator chloride channel pore.
@en
P2093
Evagelidis A
Hanrahan JW
Linsdell P
P2860
P304
P356
10.1016/S0006-3495(00)76836-6
P407
P577
2000-06-01T00:00:00Z