Disulphonic stilbene block of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a mammalian cell line and its regulation by a critical pore residue.
about
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): THREE-DIMENSIONAL STRUCTURE AND LOCALIZATION OF A CHANNEL GATERelationship between anion binding and anion permeability revealed by mutagenesis within the cystic fibrosis transmembrane conductance regulator chloride channel porePerturbation of the pore of the cystic fibrosis transmembrane conductance regulator (CFTR) inhibits its atpase activity.Molecular and functional evidence for electrogenic and electroneutral Na(+)-HCO(3)(-) cotransporters in murine duodenum.Cystic fibrosis transmembrane conductance regulator. Structure and function of an epithelial chloride channel.Cystic fibrosis transmembrane conductance regulator (CFTR) anion binding as a probe of the poreMolecular determinants of anion selectivity in the cystic fibrosis transmembrane conductance regulator chloride channel pore.Cystic fibrosis transmembrane conductance regulator chloride channel blockers: Pharmacological, biophysical and physiological relevance.Human SLC4A11-C functions as a DIDS-stimulatable H⁺(OH⁻) permeation pathway: partial correction of R109H mutant transport.Substrates of multidrug resistance-associated proteins block the cystic fibrosis transmembrane conductance regulator chloride channel.Inhibition of heterologously expressed cystic fibrosis transmembrane conductance regulator Cl- channels by non-sulphonylurea hypoglycaemic agents.Cystic fibrosis transmembrane conductance regulator: a molecular model defines the architecture of the anion conduction path and locates a "bottleneck" in the pore.Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazidesMechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel.Adenosine triphosphate-dependent asymmetry of anion permeation in the cystic fibrosis transmembrane conductance regulator chloride channel.Halide permeation in wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channelsPermeability of wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels to polyatomic anions.Multi-Ion mechanism for ion permeation and block in the cystic fibrosis transmembrane conductance regulator chloride channelProbing an open CFTR pore with organic anion blockersVoltage-dependent gating of the cystic fibrosis transmembrane conductance regulator Cl- channel.Mutations at arginine 352 alter the pore architecture of CFTR.Biophysical and pharmacological characterization of hypotonically activated chloride currents in cortical astrocytesApplication of high-resolution single-channel recording to functional studies of cystic fibrosis mutants.CLC-0 and CFTR: chloride channels evolved from transporters.Endogenous ATP release inhibits electrogenic Na⁺ absorption and stimulates Cl⁻ secretion in MDCK cells.Architecture and functional properties of the CFTR channel pore.Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore.Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore.Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel.Cysteine-independent inhibition of the CFTR chloride channel by the cysteine-reactive reagent sodium (2-sulphonatoethyl) methanethiosulphonate.Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore.State-dependent access of anions to the cystic fibrosis transmembrane conductance regulator chloride channel pore.On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore.Interactions between impermeant blocking ions in the cystic fibrosis transmembrane conductance regulator chloride channel pore: evidence for anion-induced conformational changes.Direct comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore.Direct block of the cystic fibrosis transmembrane conductance regulator Cl(-) channel by niflumic acid.Coupled movement of permeant and blocking ions in the CFTR chloride channel pore.Two mechanisms of genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in murine cell line.Non-pore lining amino acid side chains influence anion selectivity of the human CFTR Cl- channel expressed in mammalian cell lines.CFTR Cl- channel and CFTR-associated ATP channel: distinct pores regulated by common gates.
P2860
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P2860
Disulphonic stilbene block of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a mammalian cell line and its regulation by a critical pore residue.
description
1996 nî lūn-bûn
@nan
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Disulphonic stilbene block of ...... on by a critical pore residue.
@ast
Disulphonic stilbene block of ...... on by a critical pore residue.
@en
Disulphonic stilbene block of ...... on by a critical pore residue.
@nl
type
label
Disulphonic stilbene block of ...... on by a critical pore residue.
@ast
Disulphonic stilbene block of ...... on by a critical pore residue.
@en
Disulphonic stilbene block of ...... on by a critical pore residue.
@nl
prefLabel
Disulphonic stilbene block of ...... on by a critical pore residue.
@ast
Disulphonic stilbene block of ...... on by a critical pore residue.
@en
Disulphonic stilbene block of ...... on by a critical pore residue.
@nl
P1476
Disulphonic stilbene block of ...... on by a critical pore residue.
@en
P2093
J W Hanrahan
P Linsdell
P304
P356
10.1113/JPHYSIOL.1996.SP021719
P407
P478
496 ( Pt 3)
P577
1996-11-01T00:00:00Z