Erythroid Krüppel-like factor exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny.
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Erythroid Krüppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the beta-globin locus control regionAn embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimerA tale of three fingers: the family of mammalian Sp/XKLF transcription factorsMammalian Krüppel-like factors in health and diseasesEKLF and KLF2 have compensatory roles in embryonic beta-globin gene expression and primitive erythropoiesisA global role for EKLF in definitive and primitive erythropoiesisThe erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stabilitySubcellular transport of EKLF and switch-on of murine adult beta maj globin gene transcription.Extrinsic and intrinsic control by EKLF (KLF1) within a specialized erythroid niche.Adult stage gamma-globin silencing is mediated by a promoter direct repeat element.EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiationThe biology of the mammalian Krüppel-like family of transcription factors.Krüppel-like factors: three fingers in many pies.Transcription factor EKLF (KLF1) recruitment of the histone chaperone HIRA is essential for β-globin gene expression.Activation and repression of interleukin-12 p40 transcription by erythroid Kruppel-like factor in macrophages.Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor EklfErythropoiesis: development and differentiation.Development and differentiation of the erythroid lineage in mammalsModeling murine yolk sac hematopoiesis with embryonic stem cell culture systems.Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice.Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3).The beta-globin promoter is important for recruitment of erythroid Krüppel-like factor to the locus control region in erythroid cellsThe multifunctional role of EKLF/KLF1 during erythropoiesis.Altered regulation of beta-like globin genes by a redesigned erythroid transcription factorThe embryonic origins of erythropoiesis in mammals.The DEK Oncoprotein Is a Critical Component of the EKLF/KLF1 Enhancer in Erythroid Cells.Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases.The family feud: turning off Sp1 by Sp1-like KLF proteins.Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF.EKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination.Krüppel-like zinc fingers bind to nuclear import proteins and are required for efficient nuclear localization of erythroid Krüppel-like factor.Chromatin structure and transcriptional control elements of the erythroid Krüppel-like factor (EKLF) gene.Erythroid Krüppel-like factor (EKLF) contains a multifunctional transcriptional activation domain important for inter- and intramolecular interactions.Klf1 affects DNase II-alpha expression in the central macrophage of a fetal liver erythroblastic island: a non-cell-autonomous role in definitive erythropoiesis.Neomorphic effects of the neonatal anemia (Nan-Eklf) mutation contribute to deficits throughout development.Site-specific acetylation by p300 or CREB binding protein regulates erythroid Krüppel-like factor transcriptional activity via its interaction with the SWI-SNF complex.Unanticipated repression function linked to erythroid Krüppel-like factor.GATA-1 dominantly activates a program of erythroid gene expression in factor-dependent myeloid FDCW2 cells.Activation of beta-globin promoter by erythroid Krüppel-like factor.HS5 of the human beta-globin locus control region: a developmental stage-specific border in erythroid cells.
P2860
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P2860
Erythroid Krüppel-like factor exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Erythroid Krüppel-like factor ...... mammalian erythroid ontogeny.
@en
Erythroid Krüppel-like factor ...... mammalian erythroid ontogeny.
@nl
type
label
Erythroid Krüppel-like factor ...... mammalian erythroid ontogeny.
@en
Erythroid Krüppel-like factor ...... mammalian erythroid ontogeny.
@nl
prefLabel
Erythroid Krüppel-like factor ...... mammalian erythroid ontogeny.
@en
Erythroid Krüppel-like factor ...... mammalian erythroid ontogeny.
@nl
P2093
P2860
P1476
Erythroid Krüppel-like factor ...... mammalian erythroid ontogeny.
@en
P2093
P2860
P304
P356
10.1002/(SICI)1097-0177(199607)206:3<248::AID-AJA3>3.0.CO;2-I
P577
1996-07-01T00:00:00Z