Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways.
about
Promiscuous DNA synthesis by human DNA polymerase θEvidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-linksHomologous-recombination-deficient tumours are dependent on Polθ-mediated repairDNA polymerase POLN participates in cross-link repair and homologous recombinationA genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repairDNA Polymerase θ: A Unique Multifunctional End-Joining MachineMicrohomology-mediated end joining: new players join the teamMechanism of suppression of chromosomal instability by DNA polymerase POLQExpanded roles of the Fanconi anemia pathway in preserving genomic stabilityA team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress.Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila.Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repairDNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instabilityHuman HEL308 localizes to damaged replication forks and unwinds lagging strand structuresA DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case-control study.Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase βSingle-nucleotide polymorphisms in DNA bypass polymerase genes and association with breast cancer and breast cancer subtypes among African Americans and Whites.Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining.JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity.Linking DNA polymerase theta structure and function in health and diseaseDNA polymerase POLQ and cellular defense against DNA damage.Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans.Depletion of the ER chaperone ENPL-1 sensitizes C. elegans to the anticancer drug cisplatin.Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs.HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis.Helq acts in parallel to Fancc to suppress replication-associated genome instability.Metabolism of postsynaptic recombination intermediates.Repair of DNA interstrand cross-links during S phase of the mammalian cell cycle.A DOG's View of Fanconi Anemia: Insights from C. elegans.Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.REV1 and DNA polymerase zeta in DNA interstrand crosslink repair.Comparison of two POLQ mutants reveals that a polymerase-inactive POLQ retains significant function in tolerance to etoposide and γ-irradiation in mouse B cells.Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.Methodological considerations for mutagen exposure in C. elegans.A putative Leishmania DNA polymerase theta protects the parasite against oxidative damage.A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites.Caenorhabditis elegans BUB-3 and SAN-1/MAD3 Spindle Assembly Checkpoint Components Are Required for Genome Stability in Response to Treatment with Ionizing Radiation.The DNA translocase RAD5A acts independently of the other main DNA repair pathways, and requires both its ATPase and RING domain for activity in Arabidopsis thaliana.UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.
P2860
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P2860
Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Caenorhabditis elegans POLQ-1 ...... nd cross-link repair pathways.
@en
Caenorhabditis elegans POLQ-1 ...... nd cross-link repair pathways.
@nl
type
label
Caenorhabditis elegans POLQ-1 ...... nd cross-link repair pathways.
@en
Caenorhabditis elegans POLQ-1 ...... nd cross-link repair pathways.
@nl
prefLabel
Caenorhabditis elegans POLQ-1 ...... nd cross-link repair pathways.
@en
Caenorhabditis elegans POLQ-1 ...... nd cross-link repair pathways.
@nl
P2093
P1433
P1476
Caenorhabditis elegans POLQ-1 ...... nd cross-link repair pathways.
@en
P2093
Diego M Muzzini
Giuseppe Cassata
Simon J Boulton
P304
P356
10.1016/J.DNAREP.2008.03.021
P577
2008-05-09T00:00:00Z