Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
about
The PI3K pathway as drug target in human cancerAn integrated genomic analysis of human glioblastoma multiformeComprehensive genomic characterization defines human glioblastoma genes and core pathwaysIdentification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastomaSirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsPI3K and AKT: Unfaithful Partners in CancerWill kinase inhibitors make it as glioblastoma drugs?Structure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and SelectivityTargeting the phosphoinositide 3-kinase pathway in cancerRNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation.Cancer-derived mutations in the regulatory subunit p85alpha of phosphoinositide 3-kinase function through the catalytic subunit p110alphaPhosphatidylinositol 3-kinase: the oncoprotein.Phase II study of PX-866 in recurrent glioblastoma.PIK3R1 (p85α) is somatically mutated at high frequency in primary endometrial cancerIdentification of mutations in distinct regions of p85 alpha in urothelial cancer.Akt signaling is required for glioblastoma maintenance in vivoTargeting class IA PI3K isoforms selectively impairs cell growth, survival, and migration in glioblastoma.miR-26a and miR-214 down-regulate expression of the PTEN gene in chronic lymphocytic leukemia, but not PTEN mutation or promoter methylation.Tocotrienols fight cancer by targeting multiple cell signaling pathways.Emerging insights into the molecular and cellular basis of glioblastoma.Mutation of the PIK3CA oncogene in human cancersp110δ PI3 kinase pathway: emerging roles in cancer.Genetic heterogeneity in Finnish hereditary prostate cancer using ordered subset analysisRES-529: a PI3K/AKT/mTOR pathway inhibitor that dissociates the mTORC1 and mTORC2 complexes.Class I PI3K in oncogenic cellular transformation.Molecular neuropathology of gliomas.The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.Novel inhibitors of the PI3K family.New phosphatidylinositol 3-kinase inhibitors for cancer.Advances in malignant glioma drug discovery.Targeting the PI3K pathway for cancer therapy.Therapeutic targeting of EGFR-activated metabolic pathways in glioblastoma.PI3K in cancer-stroma interactions: bad in seed and ugly in soil.Genetic alterations in glioma.EGFR-dependent mechanisms in glioblastoma: towards a better therapeutic strategy.Chromosomal Instability and Phosphoinositide Pathway Gene Signatures in Glioblastoma MultiformeGene expression profiling analysis contributes to understanding the association between non-syndromic cleft lip and palate, and cancer.Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells.Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.
P2860
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P2860
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
description
2004 nî lūn-bûn
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2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
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2004年學術文章
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2004年學術文章
@zh-hant
name
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
@en
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
@nl
type
label
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
@en
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
@nl
prefLabel
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
@en
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
@nl
P2093
P1433
P1476
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.
@en
P2093
Catherine L Nutt
David N Louis
Gayatry Mohapatra
Masahiro Mizoguchi
P304
P356
10.1111/J.1750-3639.2004.TB00080.X
P577
2004-10-01T00:00:00Z